ARACHIDYL ALCOHOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H42O
Molecular Weight	298.5469
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCCCCCCCCO

InChI

InChIKey=BTFJIXJJCSYFAL-UHFFFAOYSA-N

InChI=1S/C20H42O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21/h21H,2-20H2,1H3

HIDE SMILES / InChI

Molecular Formula	C20H42O
Molecular Weight	298.5469
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Comparison of the effects of policosanol and atorvastatin on lipid profile and platelet aggregation in patients with dyslipidaemia and type 2 diabetes mellitus.	2003	17535079
Effects of rice policosanol on serum lipoproteins, homocysteine, fibrinogen and C-reactive protein in hypercholesterolaemic patients.	2005	17532716
A comparison of the effects of D-003 and policosanol (5 and 10 mg/day) in patients with type II hypercholesterolemia: a randomized, double-blinded study.	2005	16444910
Policosanol has no antioxidant activity in human low-density lipoprotein but increases excretion of bile acids in hamsters.	2005 Aug 10	16076108
Spectroscopic study on the photophysical properties of novel lanthanide complexes with long chain mono-L phthalate (L=hexadecyl, octadecyl and eicosyl).	2005 Nov	16257724
[A randomized, double-blind, placebo-controlled study of the antilipemic efficacy and tolerability of food supplement policosanol in patients with moderate hypercholesterolemia].	2005 Nov-Dec	16583932
Protective effect of policosanol on atherosclerotic plaque on aortas in monkeys.	2005 Sep-Oct	16099319
Toward prevention of Alzheimers disease--potential nutraceutical strategies for suppressing the production of amyloid beta peptides.	2006	16828233
Adjuvant strategies for prevention of glomerulosclerosis.	2006	16828231
Down-regulation of microglial activation may represent a practical strategy for combating neurodegenerative disorders.	2006	16513287
PolicosanolPlus and Neuroprevin ameliorate pesticide-mediated inhibition of neurite outgrowth and neurite degeneration.	2006 Dec	17136002
Effects of policosanol on patients with ischemic stroke: a pilot open study.	2006 Fall	17004902
Policosanol content and composition in perilla seeds.	2006 Jul 26	16848517
Toward a core nutraceutical program for cancer management.	2006 Jun	16685077
Interfacial rheology and structure of straight-chain and branched fatty alcohol mixtures.	2006 Jun 6	16732659
[Chemical constituents analysis of policosanol by GC and GC/MS].	2006 Mar	16830483
New policosanol product combines natural cholesterol lowering with omega-3 fatty acids to lower CV risk.	2006 Mar-Apr	16733605
Effects of a policosanol supplement on serum lipid concentrations in hypercholesterolaemic and heterozygous familial hypercholesterolaemic subjects.	2006 May	16611388
Effect of policosanol on lipid levels among patients with hypercholesterolemia or combined hyperlipidemia: a randomized controlled trial.	2006 May 17	16705107
Comparative lipid-lowering effects of policosanol and atorvastatin: a randomized, parallel, double-blind, placebo-controlled trial.	2006 Nov	17070175
Complementary and alternative therapies for the management of dyslipidemia.	2006 Nov	17047144
Policosanol: a sweet nothing for high cholesterol.	2006 Sep	17131532
Policosanol inhibits cholesterol synthesis in hepatoma cells by activation of AMP-kinase.	2006 Sep	16714400
Eulipidemic effects of berberine administered alone or in combination with other natural cholesterol-lowering agents. A single-blind clinical investigation.	2007	17341006
Competency-based evaluation tools for integrative medicine training in family medicine residency: a pilot study.	2007 Apr 18	17442108
Rice policosanol does not have any effects on blood coagulation factors in hypercholesterolemic patients.	2007 Dec	18217459
Dietary supplements for the prevention and treatment of coronary artery disease.	2007 Jan-Feb	17309382
Comparison of various extraction methods for policosanol from rice bran wax and establishment of chromatographic fingerprint of policosanol.	2007 Jul 11	17564456
Concentrated oat beta-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial.	2007 Mar 26	17386092
Photophysical properties of novel ternary lanthanide complexes with long chain mono-L cis-butene dicarboxylate (L = hexadecyl, octadecyl and eicosyl) and 2,2'-bipyridyl (or 1,10-phenanthroline).	2007 May	17440798
The odor of origin: kinship and geographical distance are reflected in the marking pheromone of male beewolves (Philanthus triangulum F., Hymenoptera, Crabronidae).	2007 Oct 10	17927833
Protective effect of policosanol on endothelium and intimal thickness induced by forceps in rabbits.	2007 Sep	17887938
Lack of effect of sugar cane policosanol on plasma cholesterol in Golden Syrian hamsters.	2007 Sep	17123537
Role of peroxisome proliferator-activated receptor alpha in the control of cyclooxygenase 2 and vascular endothelial growth factor: involvement in tumor growth.	2008	18670614
Effects of D-003, a mixture of very long chain saturated fatty acids, and policosanol on in vivo lipid peroxidation in rats.	2008	18488809
Sugar cane policosanol failed to lower plasma cholesterol in primitive, diet-resistant hypercholesterolaemia: a double blind, controlled study.	2008 Apr	18514906
Effects of emulsified policosanols with different chain lengths on cholesterol metabolism in heterozygous LDL receptor-deficient mice.	2008 Apr	18162663
Changes in cholesterol kinetics following sugar cane policosanol supplementation: a randomized control trial.	2008 Apr 30	18447941
Lack of effect of sugar cane and sunflower seed policosanols on plasma cholesterol in rabbits.	2008 Aug	18978167
Does the solid-liquid crystal phase transition provoke the spin-state change in spin-crossover metallomesogens?	2008 Jan 30	18181626
Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo.	2008 Jul	18495798
Octacosanol isolated from Tinospora cordifolia downregulates VEGF gene expression by inhibiting nuclear translocation of NF-B and its DNA binding activity.	2008 Jul 7	18513715
Identification of chemical compounds from the leaves of Leea indica.	2008 Jun	18515230
Effects of policosanol (10 mg/d) versus aspirin (100 mg/d) in patients with intermittent claudication: a 10-week, randomized, comparative study.	2008 Jun-Jul	18388038
Novel molecular precursor of lanthanide complexes with long chain mono cis-butene dicarboxylate to the controlled synthesis of Y2O3:Eu3+ phosphors.	2008 Mar	18468122
Octacosanol attenuates disrupted hepatic reactive oxygen species metabolism associated with acute liver injury progression in rats intoxicated with carbon tetrachloride.	2008 Mar	18385828
Effect of sugar cane policosanol on lipid profile in primary hypercholesterolemia.	2008 Mar	18167048
COX-1, and not COX-2 activity, regulates airway function: relevance to aspirin-sensitive asthma.	2008 Nov	18753249
Gas chromatographic determination of high molecular weight alcohols from policosanol in omega-3 fish oil by acylation with acetyl chloride.	2008 Sep-Oct	18980113
Antiatherosclerotic function of Kokuto, Okinawan noncentrifugal cane sugar.	2009 Jan 14	19072226

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:10:53 UTC 2023` Edited by `admin` on `Fri Dec 15 17:10:53 UTC 2023`
Record UNII	1QR1QRA9BU
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ARACHIDYL ALCOHOL

Official Name

English

EICOSYL ALCOHOL

Systematic Name

English

ARACHIDIC ALCOHOL

Common Name

English

ARACHIDYL ALCOHOL [INCI]

Common Name

English

ARACHIDYL ALCOHOL [USP-RS]

Common Name

English

ARACHIC ALCOHOL

Common Name

English

1-EICOSANOL [HSDB]

Common Name

English

1-ICOSANOL

Systematic Name

English

1-EICOSANOL

Systematic Name

English

NSC-120887

Code

English

Code System Code Type Description

PUBCHEM

12404