U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C37H40N2O8S
Molecular Weight 672.787
Optical Activity UNSPECIFIED
Defined Stereocenters 8 / 8
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CORTISUZOL

SMILES

[H][C@@]12C[C@@H](C)[C@](O)(C(=O)COC(=O)C3=CC(=CC=C3)S(O)(=O)=O)[C@@]1(C)C[C@H](O)[C@@]4([H])[C@@]2([H])C=C(C)C5=CC6=C(C[C@]45C)C=NN6C7=CC=CC=C7

InChI

InChIKey=ZKIDWWQMNXGYHV-BYJSBFAFSA-N
InChI=1S/C37H40N2O8S/c1-21-13-27-29-14-22(2)37(43,32(41)20-47-34(42)23-9-8-12-26(15-23)48(44,45)46)36(29,4)18-31(40)33(27)35(3)17-24-19-38-39(30(24)16-28(21)35)25-10-6-5-7-11-25/h5-13,15-16,19,22,27,29,31,33,40,43H,14,17-18,20H2,1-4H3,(H,44,45,46)/t22-,27+,29+,31+,33-,35+,36+,37+/m1/s1

HIDE SMILES / InChI
Cortisuzol is a glucocorticoid corticosteroid, discovered by the French company Roussel Uclaf, and claimed to have anti-inflammatory activity in a number of clinical case reports.

Approval Year

Name Type Language
CORTISUZOL
INN  
INN  
Official Name English
2'H-PREGNA-2,4,6-TRIENO(3,2-C)PYRAZOL-20-ONE, 11,17-DIHYDROXY-6,16-DIMETHYL-2'-PHENYL-21-((3-SULFOBENZOYL)OXY)-, (11.BETA.,16.ALPHA.)-
Common Name English
11.BETA.,17,21-TRIHYDROXY-6,16.ALPHA.-DIMETHYL-2'-PHENYL-2'H-PREGNA-2,4,6-TRIENO(3,2-C)PYRAZOL-20-ONE 21-(M-SULFOBENZOATE)
Common Name English
cortisuzol [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C521
Created by admin on Fri Dec 15 16:30:50 GMT 2023 , Edited by admin on Fri Dec 15 16:30:50 GMT 2023
Code System Code Type Description
EVMPD
SUB06808MIG
Created by admin on Fri Dec 15 16:30:50 GMT 2023 , Edited by admin on Fri Dec 15 16:30:50 GMT 2023
PRIMARY
EPA CompTox
DTXSID60198831
Created by admin on Fri Dec 15 16:30:50 GMT 2023 , Edited by admin on Fri Dec 15 16:30:50 GMT 2023
PRIMARY
ChEMBL
CHEMBL2106054
Created by admin on Fri Dec 15 16:30:50 GMT 2023 , Edited by admin on Fri Dec 15 16:30:50 GMT 2023
PRIMARY
FDA UNII
1PA76KJ99Y
Created by admin on Fri Dec 15 16:30:50 GMT 2023 , Edited by admin on Fri Dec 15 16:30:50 GMT 2023
PRIMARY
WIKIPEDIA
Cortisuzol
Created by admin on Fri Dec 15 16:30:50 GMT 2023 , Edited by admin on Fri Dec 15 16:30:50 GMT 2023
PRIMARY
NCI_THESAURUS
C77411
Created by admin on Fri Dec 15 16:30:50 GMT 2023 , Edited by admin on Fri Dec 15 16:30:50 GMT 2023
PRIMARY
PUBCHEM
3037936
Created by admin on Fri Dec 15 16:30:50 GMT 2023 , Edited by admin on Fri Dec 15 16:30:50 GMT 2023
PRIMARY
SMS_ID
100000084269
Created by admin on Fri Dec 15 16:30:50 GMT 2023 , Edited by admin on Fri Dec 15 16:30:50 GMT 2023
PRIMARY
CAS
50801-44-0
Created by admin on Fri Dec 15 16:30:50 GMT 2023 , Edited by admin on Fri Dec 15 16:30:50 GMT 2023
PRIMARY
INN
3381
Created by admin on Fri Dec 15 16:30:50 GMT 2023 , Edited by admin on Fri Dec 15 16:30:50 GMT 2023
PRIMARY