CORTISUZOL

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C37H40N2O8S
Molecular Weight	672.787
Optical Activity	UNSPECIFIED
Defined Stereocenters	8 / 8
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12C[C@@H](C)[C@](O)(C(=O)COC(=O)C3=CC(=CC=C3)S(O)(=O)=O)[C@@]1(C)C[C@H](O)[C@@]4([H])[C@@]2([H])C=C(C)C5=CC6=C(C[C@]45C)C=NN6C7=CC=CC=C7

InChI

InChIKey=ZKIDWWQMNXGYHV-BYJSBFAFSA-N

InChI=1S/C37H40N2O8S/c1-21-13-27-29-14-22(2)37(43,32(41)20-47-34(42)23-9-8-12-26(15-23)48(44,45)46)36(29,4)18-31(40)33(27)35(3)17-24-19-38-39(30(24)16-28(21)35)25-10-6-5-7-11-25/h5-13,15-16,19,22,27,29,31,33,40,43H,14,17-18,20H2,1-4H3,(H,44,45,46)/t22-,27+,29+,31+,33-,35+,36+,37+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C37H40N2O8S
Molecular Weight	672.787
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	7 / 8
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://patents.google.com/patent/US3803132A/en?q=US3803132

Cortisuzol is a glucocorticoid corticosteroid, discovered by the French company Roussel Uclaf, and claimed to have anti-inflammatory activity in a number of clinical case reports.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:30:50 UTC 2023` Edited by `admin` on `Fri Dec 15 16:30:50 UTC 2023`
Record UNII	1PA76KJ99Y
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CORTISUZOL

Official Name

English

2'H-PREGNA-2,4,6-TRIENO(3,2-C)PYRAZOL-20-ONE, 11,17-DIHYDROXY-6,16-DIMETHYL-2'-PHENYL-21-((3-SULFOBENZOYL)OXY)-, (11.BETA.,16.ALPHA.)-

Common Name

English

11.BETA.,17,21-TRIHYDROXY-6,16.ALPHA.-DIMETHYL-2'-PHENYL-2'H-PREGNA-2,4,6-TRIENO(3,2-C)PYRAZOL-20-ONE 21-(M-SULFOBENZOATE)

Common Name

English

cortisuzol [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C521