Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C23H29N3O3.ClH |
| Molecular Weight | 431.956 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
| Stereo Comments | Assumed racemic |
SHOW SMILES / InChI
SMILES
Cl.CCN(CC)CC(O)CNC(=O)C1=C(OC)C2=C(C=CC=C2)N1C3=CC=CC=C3
InChI
InChIKey=QFDGNFAPAMWAAM-UHFFFAOYSA-N
InChI=1S/C23H29N3O3.ClH/c1-4-25(5-2)16-18(27)15-24-23(28)21-22(29-3)19-13-9-10-14-20(19)26(21)17-11-7-6-8-12-17;/h6-14,18,27H,4-5,15-16H2,1-3H3,(H,24,28);1H
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Determination of eproxindine hydrochloride in human plasma by capillary gas chromatography. | 1988-05-13 |
|
| Effects of KC 3791 on sodium and potassium channels in frog node of Ranvier. | 1986-12 |
|
| Use-dependent blockade of sodium channels by local anaesthetics and antiarrhythmic drugs. Effects of chloramine-T and calcium ions. | 1986 |
|
| The role of inactivation in the cumulative blockage of voltage-dependent sodium channels by local anesthetics and antiarrythmics. | 1984-12 |
Patents
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2435614/
Eproxindine (KC 3791) When applied externally to the node of Ranvier, KC 3791 (KC) at concentrations of 10-100 uM produced both tonic and cumulative (use-dependent) inhibition of sodium currents.
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158872
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1H0DBU29HS
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DTXSID801006380
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85793-72-2
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admin on Mon Mar 31 17:46:24 GMT 2025 , Edited by admin on Mon Mar 31 17:46:24 GMT 2025
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ACTIVE MOIETY
SUBSTANCE RECORD