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Details

Stereochemistry ACHIRAL
Molecular Formula C12H15N3O2S2
Molecular Weight 297.396
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GLYBUZOLE

SMILES

CC(C)(C)C1=NN=C(NS(=O)(=O)C2=CC=CC=C2)S1

InChI

InChIKey=NMWQEPCLNXHPDX-UHFFFAOYSA-N
InChI=1S/C12H15N3O2S2/c1-12(2,3)10-13-14-11(18-10)15-19(16,17)9-7-5-4-6-8-9/h4-8H,1-3H3,(H,14,15)

HIDE SMILES / InChI

Description

Glybuzole is a sulfonamide derivative with antihyperglycemic activity is used as antidiabetic. Glybuzole is able to lower blood glucose levels by increasing the release of insulin from pancreatic beta cells.

Approval Year

Unknown
139,594

Targets

Primary TargetPharmacologyConditionPotency
insulin secretion
8
Activator
1,430

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diabetes mellitus
91
 Primary
Preclinical
Gludiase

PubMed

Patents

20010014340
11

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Oral
In Vitro Use Guide
Unknown
ACTIVE MOIETY
Structure of GLYBUZOLE
NIH
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