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Details

Stereochemistry ACHIRAL
Molecular Formula C12H15N3O2S2
Molecular Weight 297.396
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GLYBUZOLE

SMILES

CC(C)(C)C1=NN=C(NS(=O)(=O)C2=CC=CC=C2)S1

InChI

InChIKey=NMWQEPCLNXHPDX-UHFFFAOYSA-N
InChI=1S/C12H15N3O2S2/c1-12(2,3)10-13-14-11(18-10)15-19(16,17)9-7-5-4-6-8-9/h4-8H,1-3H3,(H,14,15)

HIDE SMILES / InChI
Molecular Formula C12H15N3O2S2
Molecular Weight 297.396
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Glybuzole is a sulfonamide derivative with antihyperglycemic activity is used as antidiabetic. Glybuzole is able to lower blood glucose levels by increasing the release of insulin from pancreatic beta cells.

Approval Year

Unknown
149,124

Targets

Primary TargetPharmacologyConditionPotency
insulin secretion
8
Activator
1,447

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diabetes mellitus
93
 Primary
Preclinical
Gludiase

PubMed

Patents

20010014340
11

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
1DJ2B68M2C
Record Status Validated (UNII)
Record Version
NIH
NCATS
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