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Details

Stereochemistry ACHIRAL
Molecular Formula C18H19N.ClH
Molecular Weight 285.811
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BENZOCTAMINE HYDROCHLORIDE

SMILES

Cl.CNCC12CCC(C3=CC=CC=C13)C4=CC=CC=C24

InChI

InChIKey=NZPJYSIIKYJREH-UHFFFAOYSA-N
InChI=1S/C18H19N.ClH/c1-19-12-18-11-10-13(14-6-2-4-8-16(14)18)15-7-3-5-9-17(15)18;/h2-9,13,19H,10-12H2,1H3;1H

HIDE SMILES / InChI

Description

Benzoctamine (Tacitin), a psychotropic drug, known to exert in man an anti-anxiety effect. Its action also was studied when given as a hypnotic or sedative in patients with respiratory failure. Benzoctamine decreases 5-HT turnover in the brain and this action may play a role in the anti-anxiety effect of the drug.

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Sodium-dependent serotonin transporter
40
Target ID: P31645
Gene ID: 6532.0
Gene Symbol: SLC6A4
Target Organism: Homo sapiens (Human)
Inhibitor
8297
Antagonist
2778
 7.0 null [pIC50]
PubMed

PubMed

TitleDatePubMed
Benzoctamine. A preliminary report on a new sedative drug.
1974 Nov
Synthesis of 2-(9,10-dihydro-9,10-propanoanthracen-9-yl)-N-methylethanaminevia a [4+2] cycloaddition.
2010 Jun 9

Sample Use Guides

In Vivo Use Guide
10 mg of benzoctamine and 20 mg
Route of Administration: Oral
Name Type Language
BENZOCTAMINE HYDROCHLORIDE
MART.   MI   USAN   WHO-DD  
USAN  
Official Name English
BENZOCTAMINE HYDROCHLORIDE [USAN]
Common Name English
BENZOCTAMINE HYDROCHLORIDE [MART.]
Common Name English
BENZOCTAMINE HYDROCHLORIDE [MI]
Common Name English
Benzoctamine hydrochloride [WHO-DD]
Common Name English
BENZOCTAMINE HCL
Common Name English
9,10-ETHANOANTHRACENE-9(10H)-METHANAMINE, N-METHYL-, HYDROCHLORIDE
Systematic Name English
BA-30803
Code English
N-Methyl-9,10-ethanoanthracene-9(10H)-methylamine hydrochloride
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C28197
Created by admin on Fri Dec 15 15:05:44 GMT 2023 , Edited by admin on Fri Dec 15 15:05:44 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C83546
Created by admin on Fri Dec 15 15:05:44 GMT 2023 , Edited by admin on Fri Dec 15 15:05:44 GMT 2023
PRIMARY
CAS
10085-81-1
Created by admin on Fri Dec 15 15:05:44 GMT 2023 , Edited by admin on Fri Dec 15 15:05:44 GMT 2023
PRIMARY
ECHA (EC/EINECS)
233-216-0
Created by admin on Fri Dec 15 15:05:44 GMT 2023 , Edited by admin on Fri Dec 15 15:05:44 GMT 2023
PRIMARY
MESH
C100247
Created by admin on Fri Dec 15 15:05:44 GMT 2023 , Edited by admin on Fri Dec 15 15:05:44 GMT 2023
PRIMARY
FDA UNII
1C280S920Q
Created by admin on Fri Dec 15 15:05:44 GMT 2023 , Edited by admin on Fri Dec 15 15:05:44 GMT 2023
PRIMARY
ChEMBL
CHEMBL2110603
Created by admin on Fri Dec 15 15:05:44 GMT 2023 , Edited by admin on Fri Dec 15 15:05:44 GMT 2023
PRIMARY
PUBCHEM
66275
Created by admin on Fri Dec 15 15:05:44 GMT 2023 , Edited by admin on Fri Dec 15 15:05:44 GMT 2023
PRIMARY
SMS_ID
100000085000
Created by admin on Fri Dec 15 15:05:44 GMT 2023 , Edited by admin on Fri Dec 15 15:05:44 GMT 2023
PRIMARY
EPA CompTox
DTXSID60143543
Created by admin on Fri Dec 15 15:05:44 GMT 2023 , Edited by admin on Fri Dec 15 15:05:44 GMT 2023
PRIMARY
DRUG BANK
DB09021
Created by admin on Fri Dec 15 15:05:44 GMT 2023 , Edited by admin on Fri Dec 15 15:05:44 GMT 2023
PRIMARY
EVMPD
SUB00723MIG
Created by admin on Fri Dec 15 15:05:44 GMT 2023 , Edited by admin on Fri Dec 15 15:05:44 GMT 2023
PRIMARY
MERCK INDEX
m2359
Created by admin on Fri Dec 15 15:05:44 GMT 2023 , Edited by admin on Fri Dec 15 15:05:44 GMT 2023
PRIMARY Merck Index
ACTIVE MOIETY
Structure of BENZOCTAMINE
NIH
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