BENZOCTAMINE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H19N.ClH
Molecular Weight	285.811
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CNCC12CCC(C3=CC=CC=C13)C4=CC=CC=C24

InChI

InChIKey=NZPJYSIIKYJREH-UHFFFAOYSA-N

InChI=1S/C18H19N.ClH/c1-19-12-18-11-10-13(14-6-2-4-8-16(14)18)15-7-3-5-9-17(15)18;/h2-9,13,19H,10-12H2,1H3;1H

HIDE SMILES / InChI

Molecular Formula	C18H19N
Molecular Weight	249.3502
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4480288 | https://www.ncbi.nlm.nih.gov/pubmed/20791872

Benzoctamine (Tacitin), a psychotropic drug, known to exert in man an anti-anxiety effect. Its action also was studied when given as a hypnotic or sedative in patients with respiratory failure. Benzoctamine decreases 5-HT turnover in the brain and this action may play a role in the anti-anxiety effect of the drug.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Sodium-dependent serotonin transporter 40 Target ID: P31645 Gene ID: 6532.0 Gene Symbol: SLC6A4 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/4480288	Inhibitor 8297
Serotonin 2 (5-HT2) receptor 87 Target ID: CHEMBL2095200 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6738305	Antagonist 2778		7.0 null [pIC50]

PubMed

Title	Date	PubMed
Benzoctamine. A preliminary report on a new sedative drug.	1974 Nov	4479725
Synthesis of 2-(9,10-dihydro-9,10-propanoanthracen-9-yl)-N-methylethanaminevia a [4+2] cycloaddition.	2010 Jun 9	20657434

Sample Use Guides

In Vivo Use Guide

10 mg of benzoctamine and 20 mg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:05:44 GMT 2023` Edited by `admin` on `Fri Dec 15 15:05:44 GMT 2023`
Record UNII	1C280S920Q
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BENZOCTAMINE HYDROCHLORIDE

Official Name

English

BENZOCTAMINE HYDROCHLORIDE [USAN]

Common Name

English

BENZOCTAMINE HYDROCHLORIDE [MART.]

Common Name

English

BENZOCTAMINE HYDROCHLORIDE [MI]

Common Name

English

Benzoctamine hydrochloride [WHO-DD]

Common Name

English

BENZOCTAMINE HCL

Common Name

English

9,10-ETHANOANTHRACENE-9(10H)-METHANAMINE, N-METHYL-, HYDROCHLORIDE

Systematic Name

English

BA-30803

Code

English

N-Methyl-9,10-ethanoanthracene-9(10H)-methylamine hydrochloride

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28197