OPC-14523

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H28ClN3O2
Molecular Weight	413.94
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of OPC-14523

SMILES

COC1=C2CCC(=O)N(CCCN3CCN(CC3)C4=CC=CC(Cl)=C4)C2=CC=C1

InChI

InChIKey=TZZGTNZBLPCBIS-UHFFFAOYSA-N

InChI=1S/C23H28ClN3O2/c1-29-22-8-3-7-21-20(22)9-10-23(28)27(21)12-4-11-25-13-15-26(16-14-25)19-6-2-5-18(24)17-19/h2-3,5-8,17H,4,9-16H2,1H3

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

Show entries

Title	Date	PubMed
Potential antidepressant activity of sigma ligands.	2003 Nov-Dec	14730086
Effects of the potential antidepressant OPC-14523 [1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2-quinolinone monomethanesulfonate] a combined sigma and 5-HT1A ligand: modulation of neuronal activity in the dorsal raphe nucleus.	2004 Aug	15044555
Behavioral pharmacology of sigma-ligands.	2004 Nov	15547784
Effects of OPC-14523, a combined sigma and 5-HT1a ligand, on pre- and post-synaptic 5-HT1a receptors.	2007 Jan	16533864

Showing 1 to 4 of 4 entries

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Name

Type

Language

OPC-14523

Code

English

OPC-14523 FREE BASE

Preferred Name

English

1-(3-(4-(3-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-5-METHOXY-3,4-DIHYDRO-2-QUINOLINONE

Systematic Name

English

2(1H)-QUINOLINONE, 1-(3-(4-(3-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-3,4-DIHYDRO-5-METHOXY-

Systematic Name

English

Showing 1 to 4 of 4 entries

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Code System

Code

Type

Description

FDA UNII

1981OTB4DS

PRIMARY

PUBCHEM

9892540

PRIMARY

DRUG BANK

DB05422

PRIMARY

CAS

145969-30-8

PRIMARY

Showing 1 to 4 of 4 entries

ACTIVE MOIETY


					1981OTB4DS

OPC-14523

SALT/SOLVATE (PARENT)


					OV3VP43XU4

OPC-14523 HYDROCHLORIDE

SALT/SOLVATE (PARENT)


					H9J1LZ3AAH

OPC-14523 MESYLATE