OMOCONAZOLE NITRATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H17Cl3N2O2.HNO3
Molecular Weight	486.733
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O[N+]([O-])=O.C\C(N1C=CN=C1)=C(\OCCOC2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3Cl

InChI

InChIKey=BNDOPUYTWJQTOE-VSOKSMTPSA-N

InChI=1S/C20H17Cl3N2O2.HNO3/c1-14(25-9-8-24-13-25)20(18-7-4-16(22)12-19(18)23)27-11-10-26-17-5-2-15(21)3-6-17;2-1(3)4/h2-9,12-13H,10-11H2,1H3;(H,2,3,4)/b20-14-;

HIDE SMILES / InChI

Description
Sources: http://www.onmeda.fr/medicament/fongamil-93327055.html

Omoconazole is an azole antifungal drug, is used to treat candidiasis; dermatophytes and Pityriasis Versicolor

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Candida infections 20 Sources: http://www.onmeda.fr/medicament/fongamil-93327055.html	Curative	Approved 8429	Unknown Approved Use Unknown
Dermatomycosis 20 Sources: http://www.onmeda.fr/medicament/fongamil-93327055.html	Curative	Approved 8429	Unknown Approved Use Unknown
Pityriasis versicolor 4 Sources: http://www.onmeda.fr/medicament/fongamil-93327055.html	Curative	Approved 8429	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Ultrastructural alterations of Candida albicans induced by a new imidazole antimycotic omoconazole nitrate.	1997	9194038

Patents

Sample Use Guides

In Vivo Use Guide

Cream; Topical; Omoconazole Nitrate 1%

Route of Administration: Topical

In Vitro Use Guide

The treatment of growing Candida cultures with fungistatic doses (0.4 to 4 micrograms/ml) of omoconazole nitrate (OMZ) produced the formation of a chain or cluster of cells. Thickening of the cell wall and accumulation of electrondense vesicles in the wall were clearly observed

Name

Type

Language

OMOCONAZOLE NITRATE

Official Name

English

OMOCONAZOLE NITRATE [JAN]

Common Name

English

Omoconazole nitrate [WHO-DD]

Common Name

English

OMOCONAZOLE NITRATE [MI]

Common Name

English

(Z)-1-(2,4-DICHLORO-.BETA.-(2-(P-CHLOROPHENOXY)ETHOXY)-.ALPHA.-METHYLSTYRYL)IMIDAZOLE MONONITRATE

Common Name

English

1H-IMIDAZOLE, 1-(2-(2-(4-CHLOROPHENOXY)ETHOXY)-2-(2,4-DICHLOROPHENYL)-1-METHYLETHENYL)-, (Z)-, MONONITRATE

Common Name

English

OMOCONAZOLE MONONITRATE

Common Name

English

OMOCONAZOLE NITRATE [MART.]

Common Name

English

OMOCONAZOLE NITRATE [USAN]

Common Name

English

10 80 07

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C514