Details
| Stereochemistry | MIXED |
| Molecular Formula | C13H11AsN6O4S2.2K |
| Molecular Weight | 532.512 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 0 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[K+].[K+].NC1=NC(NC2=CC=C(C=C2)[As]3SC(C(S3)C([O-])=O)C([O-])=O)=NC(N)=N1
InChI
InChIKey=PHCMFHVCRUCADN-UHFFFAOYSA-L
InChI=1S/C13H13AsN6O4S2.2K/c15-11-18-12(16)20-13(19-11)17-6-3-1-5(2-4-6)14-25-7(9(21)22)8(26-14)10(23)24;;/h1-4,7-8H,(H,21,22)(H,23,24)(H5,15,16,17,18,19,20);;/q;2*+1/p-2
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [POTASSIUM MELARSONYL IN THE TREATMENT OF HUMAN ONCHOCERCIASIS. PRELIMINARY NOTE. FINDINGS AFTER 10 MONTHS OF OBSERVATION]. | 1964 May-Jul |
|
| The effects of drugs on Onchocerca volvulus. 4. Trials of melarsonyl potassium. | 1970 |
|
| Synthesis and in vitro anthelmintic properties of some new dithiaarsanes. | 1999 Nov |
Sample Use Guides
The effects of the arsenical drug melarsonyl potassium on Onchocerca volvulus were investigated in patients in Cameroon infected with the Cameroon forest and Sudan savanna strains of the parasite. Two intramuscular dosage schedules were tested: the first comprised 4 consecutive daily doses of 200 mg repeated once after a 10-14 day interval, i.e., 2 (4x200 mg). The second was a single dose schedule at 7.1 mg/kg-10 mg/kg, with a maximum of 500 mg.
Route of Administration:
Intramuscular
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SUB08720MIG
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C166459
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100000081465
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236-405-6
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1484SU81EQ
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DTXSID70928181
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1256
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16173-18-5
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13355-00-5
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25907
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ACTIVE MOIETY
SUBSTANCE RECORD
