Stereochemistry | ABSOLUTE |
Molecular Formula | C15H16O5 |
Molecular Weight | 276.2845 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC=C2C=CC(=O)OC2=C1[C@H](O)[C@@H](O)C(C)=C
InChI
InChIKey=DKEANOQWICTXTP-KBPBESRZSA-N
InChI=1S/C15H16O5/c1-8(2)13(17)14(18)12-10(19-3)6-4-9-5-7-11(16)20-15(9)12/h4-7,13-14,17-18H,1H2,2-3H3/t13-,14-/m0/s1
Minumicrolin and murrangatin are the diastereomeric isomers. They are 8-substituted 7-methoxycoumarins isolated from Murraya species. They were found to significantly inhibit EBV-EA activation, and preserved the high viability of Raji cells, suggesting that they might be valuable anti-tumor-promoting agents. Minumicrolin showed mild butyrylcholinesterase inhibition activity. It exhibited cytotoxicity against cholangiocarcinoma cell line, KKU-100.