ESPATROPATE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H23N3O3
Molecular Weight	341.4042
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ESPATROPATE

Structure Search

SMILES

OC[C@@](N1C=CN=C1)(C(=O)O[C@H]2CN3CCC2CC3)C4=CC=CC=C4

InChI

InChIKey=MDJOZYCYNUJABP-HKUYNNGSSA-N

InChI=1S/C19H23N3O3/c23-13-19(22-11-8-20-14-22,16-4-2-1-3-5-16)18(24)25-17-12-21-9-6-15(17)7-10-21/h1-5,8,11,14-15,17,23H,6-7,9-10,12-13H2/t17-,19-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://adisinsight.springer.com/drugs/800003596 | https://link.springer.com/chapter/10.1007%2F978-94-011-4439-1_5

Espatropate (UK 88060) is an antagonist of M3 muscarinic receptors. Espatropate is a bronchodilator with anticholinergic activity. It was undergoing preclinical development with Pfizer for the treatment of asthma.

Originator

Approval Year

Name

Type

Language

UK-88060

Preferred Name

English

ESPATROPATE

Official Name

English

(R)-3-QUINUCLIDINYL (R)-.ALPHA.-(HYDROXYMETHYL)-.ALPHA.-PHENYLIMIDAZOLE-1-ACETATE

Systematic Name

English

espatropate [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29701

Created by admin on Mon Mar 31 18:28:06 GMT 2025 , Edited by admin on Mon Mar 31 18:28:06 GMT 2025

Code System Code Type Description

ChEMBL

CHEMBL2104280

Created by admin on Mon Mar 31 18:28:06 GMT 2025 , Edited by admin on Mon Mar 31 18:28:06 GMT 2025

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INN

6827

Created by admin on Mon Mar 31 18:28:06 GMT 2025 , Edited by admin on Mon Mar 31 18:28:06 GMT 2025

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PUBCHEM

208934

Created by admin on Mon Mar 31 18:28:06 GMT 2025 , Edited by admin on Mon Mar 31 18:28:06 GMT 2025

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EVMPD

SUB07239MIG

Created by admin on Mon Mar 31 18:28:06 GMT 2025 , Edited by admin on Mon Mar 31 18:28:06 GMT 2025

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FDA UNII

13MIU3750H

Created by admin on Mon Mar 31 18:28:06 GMT 2025 , Edited by admin on Mon Mar 31 18:28:06 GMT 2025

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SMS_ID

100000082360

Created by admin on Mon Mar 31 18:28:06 GMT 2025 , Edited by admin on Mon Mar 31 18:28:06 GMT 2025

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NCI_THESAURUS

C65541

Created by admin on Mon Mar 31 18:28:06 GMT 2025 , Edited by admin on Mon Mar 31 18:28:06 GMT 2025

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EPA CompTox

DTXSID301350877

Created by admin on Mon Mar 31 18:28:06 GMT 2025 , Edited by admin on Mon Mar 31 18:28:06 GMT 2025

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CAS

132829-83-5

Created by admin on Mon Mar 31 18:28:06 GMT 2025 , Edited by admin on Mon Mar 31 18:28:06 GMT 2025

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ACTIVE MOIETY


					13MIU3750H