ESPATROPATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H23N3O3
Molecular Weight	341.4042
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC[C@@](N1C=CN=C1)(C(=O)O[C@H]2CN3CCC2CC3)C4=CC=CC=C4

InChI

InChIKey=MDJOZYCYNUJABP-HKUYNNGSSA-N

InChI=1S/C19H23N3O3/c23-13-19(22-11-8-20-14-22,16-4-2-1-3-5-16)18(24)25-17-12-21-9-6-15(17)7-10-21/h1-5,8,11,14-15,17,23H,6-7,9-10,12-13H2/t17-,19-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C19H23N3O3
Molecular Weight	341.4042
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://adisinsight.springer.com/drugs/800003596 | https://link.springer.com/chapter/10.1007%2F978-94-011-4439-1_5

Espatropate (UK 88060) is an antagonist of M3 muscarinic receptors. Espatropate is a bronchodilator with anticholinergic activity. It was undergoing preclinical development with Pfizer for the treatment of asthma.

Originator

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:26:37 UTC 2023` Edited by `admin` on `Fri Dec 15 16:26:37 UTC 2023`
Record UNII	13MIU3750H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ESPATROPATE

Official Name

English

UK-88060

Code

English

(R)-3-QUINUCLIDINYL (R)-.ALPHA.-(HYDROXYMETHYL)-.ALPHA.-PHENYLIMIDAZOLE-1-ACETATE

Systematic Name

English

espatropate [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29701