Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C2H5N5O3 |
| Molecular Weight | 147.0928 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(N=O)C(=N)N[N+]([O-])=O
InChI
InChIKey=VZUNGTLZRAYYDE-UHFFFAOYSA-N
InChI=1S/C2H5N5O3/c1-6(5-8)2(3)4-7(9)10/h1H3,(H2,3,4)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Cadmium affects genes involved in growth regulation during two-stage transformation of Balb/3T3 cells. | 2002 Aug 15 |
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| Characterization of gene expression changes associated with MNNG, arsenic, or metal mixture treatment in human keratinocytes: application of cDNA microarray technology. | 2002 Dec |
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| Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells. | 2004 Aug |
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| Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality. | 2004 Dec 21 |
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| Combination of S-allylcysteine and lycopene induces apoptosis by modulating Bcl-2, Bax, Bim and caspases during experimental gastric carcinogenesis. | 2005 Aug |
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| The monofunctional alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine triggers apoptosis through p53-dependent and -independent pathways. | 2005 Jan 1 |
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| Apaf-1 deficient mouse fibroblasts are resistant to MNNG and MMS-induced apoptotic death without attenuation of Bcl-2 decline. | 2005 Sep 1 |
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| Rosiglitazone suppresses gastric carcinogenesis by up-regulating HCaRG expression. | 2008 Nov |
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| Eugenol induces apoptosis and inhibits invasion and angiogenesis in a rat model of gastric carcinogenesis induced by MNNG. | 2010 Jun 19 |
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| ICAM-1 and AMPK regulate cell detachment and apoptosis by N-methyl-N'-nitro-N-nitrosoguanidine, a widely spread environmental chemical, in human hormone-refractory prostate cancers. | 2011 Dec 15 |
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| Cyclin D1/cdk4, estrogen receptors α and β, in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat gastric carcinogenesis: immunohistochemical study. | 2011 Jun |
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| Sex-associated difference in estrogen receptor β expression in N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric cancers in rats. | 2011 Oct |
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| Quantitative and subcellular localization analysis of the nuclear isoform dUTP pyrophosphatase in alkylating agent-induced cell responses. | 2011 Sep 5 |
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| Promotion of hepatocarcinogenesis by perfluoroalkyl acids in rainbow trout. | 2012 Jan |
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| miR-21 regulates N-methyl-N-nitro-N'-nitrosoguanidine-induced gastric tumorigenesis by targeting FASLG and BTG2. | 2014 Aug 4 |
|
| The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response. | 2014 Jul |
|
| Evaluation of cytogenetic and DNA damage in human lymphocytes treated with adrenaline in vitro. | 2015 Feb |
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200-730-1
Created by
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21759
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5104
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D008769
Created by
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m7446
Created by
admin on Sat Dec 16 03:58:59 GMT 2023 , Edited by admin on Sat Dec 16 03:58:59 GMT 2023
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9369
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6261
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DTXSID2020846
Created by
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70-25-7
Created by
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12H3O2UGSF
Created by
admin on Sat Dec 16 03:58:59 GMT 2023 , Edited by admin on Sat Dec 16 03:58:59 GMT 2023
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METHYLNITRONITROSOGUANIDINE
Created by
admin on Sat Dec 16 03:58:59 GMT 2023 , Edited by admin on Sat Dec 16 03:58:59 GMT 2023
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SUBSTANCE RECORD
