ALLYL TRISULFIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H10S3
Molecular Weight	178.339
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C=CCSSSCC=C

InChI

InChIKey=UBAXRAHSPKWNCX-UHFFFAOYSA-N

InChI=1S/C6H10S3/c1-3-5-7-9-8-6-4-2/h3-4H,1-2,5-6H2

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
In vitro efficacy of a compound derived from garlic against Pneumocystis carinii.	1996 Nov	8999132
Protective effect of three diallyl sulphides against glucose-induced erythrocyte and platelet oxidation, and ADP-induced platelet aggregation.	2002 Dec 15	12676192
Diallyl trisulfide inhibits tumor necrosis factor-alpha expression in inflammed mucosa of ulcerative colitis.	2005 Aug	16110831
Microarray analysis of altered gene expression in diallyl trisulfide-treated HepG2 cells.	2005 Nov-Dec	16382202
Effects of allitridi on cell cycle arrest of human gastric cancer cells.	2005 Sep 21	16222732
A proteomic investigation into a human gastric cancer cell line BGC823 treated with diallyl trisulfide.	2006 Jun	16344271
[Effect of diallyl trisulfide on tumor necrosis factor-alpha expression and nuclear factor-KappaB activity in mice with acute lung injury induced by lipopolysaccharide].	2007 Apr	17448272
Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak.	2007 May	17513609
Allium compounds, dipropyl and dimethyl thiosulfinates as antiproliferative and differentiating agents of human acute myeloid leukemia cell lines.	2008 Dec	19707466
In vitro anti-Helicobacter pylori activity of diallyl sulphides and protocatechuic acid.	2008 Jan	17705145
Transcriptional repression and inhibition of nuclear translocation of androgen receptor by diallyl trisulfide in human prostate cancer cells.	2009 Aug 1	19622577
Neuroprotective potential of phase II enzyme inducer diallyl trisulfide.	2009 Feb	18768114
Diallylpolysulfides induce growth arrest and apoptosis.	2010 Mar	20126995
Diallyl trisulfide suppresses the adipogenesis of 3T3-L1 preadipocytes through ERK activation.	2012 Mar	22137902
Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo.	2012 May 15	22397993
Effect of diallyl trisulfide on human ovarian cancer SKOV- 3/DDP cell apoptosis.	2013	24460275
Diallyl trisulfide inhibits proliferation, invasion and angiogenesis of osteosarcoma cells by switching on suppressor microRNAs and inactivating of Notch-1 signaling.	2013 Jul	23430952
Diallyl sulfide, diallyl disulfide, and diallyl trisulfide inhibit migration and invasion in human colon cancer colo 205 cells through the inhibition of matrix metalloproteinase-2, -7, and -9 expressions.	2013 Sep	21695758
Antioxidant effects of diallyl trisulfide on high glucose-induced apoptosis are mediated by the PI3K/Akt-dependent activation of Nrf2 in cardiomyocytes.	2013 Sep 30	23453443
Allitridin reduces I Kr current by disrupting the trafficking of human ether-à-go-go-related gene channels.	2014	24504171
Keap1 cysteine 288 as a potential target for diallyl trisulfide-induced Nrf2 activation.	2014	24489685

Name

Type

Language

ALLYL TRISULFIDE

Systematic Name

English

ALLITRIDE

Common Name

English

Diallyl trisulfide [WHO-DD]

Common Name

English

DIALLYL TRISULPHIDE

Systematic Name

English

ALLITRIDUM

Common Name

English

DIALLYL TRISULFIDE [MI]

Common Name

English

DIALLYL TRISULFIDE

Systematic Name

English

DIALLYL TRISULFIDE [FHFI]

Common Name

English

FEMA NO. 3265

Code

English

DI-2-PROPENYL TRISULFIDE

Systematic Name

English

NSC-651936

Code

English

TRISULFIDE, DI-2-PROPENYL

Systematic Name

English

ALLITRIDIN

Common Name

English

Classification Tree Code System Code

JECFA EVALUATION

DIALLYL TRISULFIDE