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Details

Stereochemistry ABSOLUTE
Molecular Formula C39H45N2O6.I
Molecular Weight 764.6889
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIMETHYLTUBOCURARINE IODIDE

SMILES

[I-].COC1=CC=C2C[C@@H]3C4=C(CC[N+]3(C)C)C=C(OC)C(OC)=C4OC5=CC=C(C[C@@H]6N(C)CCC7=CC(OC)=C(OC1=C2)C=C67)C=C5

InChI

InChIKey=ZRILZUBJODJELN-LBYXUWKHSA-M
InChI=1S/C39H45N2O6.HI/c1-40-16-14-26-21-33(43-5)35-23-29(26)30(40)18-24-8-11-28(12-9-24)46-39-37-27(22-36(44-6)38(39)45-7)15-17-41(2,3)31(37)19-25-10-13-32(42-4)34(20-25)47-35;/h8-13,20-23,30-31H,14-19H2,1-7H3;1H/q+1;/p-1/t30-,31+;/m0./s1

HIDE SMILES / InChI
Dimethyltubocurarine (metocurine) is a non-depolarizing muscle relaxant. It binds to muscle acetylcholine receptor by bridging the to alpha and non-alpha subunits from the ligand binding site. Dimethyltubocurarine was used as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy.

Approval Year

Sample Use Guides

In Vivo Use Guide
Dimethyl-tubocurarine iodide is administered intravenously in isotonic sodium chloride solution for muscle relaxtion in surgery. The average initial dose is approximately 2 mg (80 units) and is injected slowly over a period of one to one and one-half minutes.
Route of Administration: Intravenous
Name Type Language
DIMETHYLTUBOCURARINE IODIDE
Common Name English
TUBOCURARANIUM, 6,6',7',12'-TETRAMETHOXY-2,2',2'-TRIMETHYL-, IODIDE
Preferred Name English
Code System Code Type Description
FDA UNII
0Q5R726FHX
Created by admin on Mon Mar 31 22:03:48 GMT 2025 , Edited by admin on Mon Mar 31 22:03:48 GMT 2025
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CAS
36653-49-3
Created by admin on Mon Mar 31 22:03:48 GMT 2025 , Edited by admin on Mon Mar 31 22:03:48 GMT 2025
PRIMARY
PUBCHEM
76957755
Created by admin on Mon Mar 31 22:03:48 GMT 2025 , Edited by admin on Mon Mar 31 22:03:48 GMT 2025
PRIMARY