Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C10H15NO2 |
| Molecular Weight | 181.2316 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC(=O)OC1(CC#C)CCCCC1
InChI
InChIKey=MIRHIEAGDGUXKL-UHFFFAOYSA-N
InChI=1S/C10H15NO2/c1-2-6-10(13-9(11)12)7-4-3-5-8-10/h1H,3-8H2,(H2,11,12)
Hexapropymate, a hypnotic/sedative drug that was available without prescription in Belgium under the trade name Merinax for the treatment of insomnia. Poisoning with hexapropymate was a serious condition that required symptomatic treatment in the intensive care unit. As a result, the drug was substituted by newer agents with improved safety profiles.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Pediatric indications for a synthetic non-barbituric hypnotic: hexapropymate]. | 1962 Dec 2 |
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| [5 cases of suspected hexapropymate poisoning]. | 1971 Jan-Feb |
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| [Effects of hexapropymate on sleep in normal humans, measured with a polygraphic method]. | 1975 Feb |
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| Biotransformation of hexapropymate in man. Part 2: Isolation and identification of metabolites. | 1984 Feb |
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| Hexapropymate self-poisoning causes severe and long-lasting clinical symptoms. | 1989 Jul-Aug |
Patents
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Code | English | ||
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| Classification Tree | Code System | Code | ||
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WHO-VATC |
QN05CM10
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WHO-ATC |
N05CM10
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NCI_THESAURUS |
C29756
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| Code System | Code | Type | Description | ||
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C001343
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CHEMBL2104292
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358-52-1
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1367
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100000083957
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SUB08032MIG
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m1186
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PRIMARY | Merck Index | ||
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Hexapropymate
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169094
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DTXSID00189329
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936
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DB13662
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9661
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206-618-9
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0J9RN2PRJ7
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C83752
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ACTIVE MOIETY
