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Details

Stereochemistry ACHIRAL
Molecular Formula C19H20ClN3O
Molecular Weight 341.835
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SARIPIDEM

SMILES

CCCC(=O)N(C)CC1=C(N=C2C=CC=CN12)C3=CC=C(Cl)C=C3

InChI

InChIKey=LIFDPEORUVTOCP-UHFFFAOYSA-N
InChI=1S/C19H20ClN3O/c1-3-6-18(24)22(2)13-16-19(14-8-10-15(20)11-9-14)21-17-7-4-5-12-23(16)17/h4-5,7-12H,3,6,13H2,1-2H3

HIDE SMILES / InChI
Synthélabo developed a saripidem (also known as SL 850274) as a potential anxiolytic agent that modulates the benzodiazepine-binding site on GABAA receptor via primary binding with ω1 subtype. Saripidem was studied in phase II clinical trials for the treatment of patients with anxiety disorders. However, information about the further development of the drug is not available.

Approval Year

PubMed

PubMed

TitleDatePubMed
Behavioural effects of novel benzodiazepine (omega) receptor agonists and partial agonists: increases in punished responding and antagonism of the pentylenetetrazole cue.
1995 Mar
A One Pot Synthesis of Novel Bioactive Tri-Substitute-Condensed-Imidazopyridines that Targets Snake Venom Phospholipase A2.
2015
Synthesis of Indolizines via Reaction of 2-Substitued Azaarenes with Enals by an Amine-NHC Relay Catalysis.
2017 Apr 21
Name Type Language
SARIPIDEM
INN  
INN  
Official Name English
saripidem [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29756
Created by admin on Sat Dec 16 16:04:07 GMT 2023 , Edited by admin on Sat Dec 16 16:04:07 GMT 2023
Code System Code Type Description
SMS_ID
100000084096
Created by admin on Sat Dec 16 16:04:07 GMT 2023 , Edited by admin on Sat Dec 16 16:04:07 GMT 2023
PRIMARY
FDA UNII
0J6174G60N
Created by admin on Sat Dec 16 16:04:07 GMT 2023 , Edited by admin on Sat Dec 16 16:04:07 GMT 2023
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WIKIPEDIA
SARIPIDEM
Created by admin on Sat Dec 16 16:04:07 GMT 2023 , Edited by admin on Sat Dec 16 16:04:07 GMT 2023
PRIMARY
NCI_THESAURUS
C74381
Created by admin on Sat Dec 16 16:04:07 GMT 2023 , Edited by admin on Sat Dec 16 16:04:07 GMT 2023
PRIMARY
INN
6932
Created by admin on Sat Dec 16 16:04:07 GMT 2023 , Edited by admin on Sat Dec 16 16:04:07 GMT 2023
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EPA CompTox
DTXSID60146110
Created by admin on Sat Dec 16 16:04:07 GMT 2023 , Edited by admin on Sat Dec 16 16:04:07 GMT 2023
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ChEMBL
CHEMBL73416
Created by admin on Sat Dec 16 16:04:07 GMT 2023 , Edited by admin on Sat Dec 16 16:04:07 GMT 2023
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CAS
103844-86-6
Created by admin on Sat Dec 16 16:04:07 GMT 2023 , Edited by admin on Sat Dec 16 16:04:07 GMT 2023
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EVMPD
SUB10451MIG
Created by admin on Sat Dec 16 16:04:07 GMT 2023 , Edited by admin on Sat Dec 16 16:04:07 GMT 2023
PRIMARY
PUBCHEM
3058746
Created by admin on Sat Dec 16 16:04:07 GMT 2023 , Edited by admin on Sat Dec 16 16:04:07 GMT 2023
PRIMARY