MK-8777

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C11H12N2O2
Molecular Weight	204.2252
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MK-8777

Structure Search

SMILES

[H][C@@]12CCCN1C(=O)C3=CC=CN=C3OC2

InChI

InChIKey=FIKUEZUFASUKAH-QMMMGPOBSA-N

InChI=1S/C11H12N2O2/c14-11-9-4-1-5-12-10(9)15-7-8-3-2-6-13(8)11/h1,4-5,8H,2-3,6-7H2/t8-/m0/s1

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Glutamate receptor ionotropic AMPA 41 Target ID: CHEMBL2096670 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22954616 \| https://www.ncbi.nlm.nih.gov/pubmed/15993447	Positive Allosteric Modulator 179

Name

Type

Language

MK-8777

Code

English

5H,7H-PYRIDO(3,2-F)PYRROLO(2,1-C)(1,4)OXAZEPIN-5-ONE, 8,9,9A,10-TETRAHYDRO-, (9AS)-

Systematic Name

English

ORG-26576

Code

English

Code System Code Type Description

PUBCHEM

13584912

Created by admin on Sat Dec 16 10:06:35 GMT 2023 , Edited by admin on Sat Dec 16 10:06:35 GMT 2023

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FDA UNII

0H1IDR8Z4F

Created by admin on Sat Dec 16 10:06:35 GMT 2023 , Edited by admin on Sat Dec 16 10:06:35 GMT 2023

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WIKIPEDIA

ORG-26576

Created by admin on Sat Dec 16 10:06:35 GMT 2023 , Edited by admin on Sat Dec 16 10:06:35 GMT 2023

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CAS

1026791-61-6

Created by admin on Sat Dec 16 10:06:35 GMT 2023 , Edited by admin on Sat Dec 16 10:06:35 GMT 2023

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EPA CompTox

DTXSID001336129

Created by admin on Sat Dec 16 10:06:35 GMT 2023 , Edited by admin on Sat Dec 16 10:06:35 GMT 2023

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ACTIVE MOIETY


					0H1IDR8Z4F

MK-8777