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Details

Stereochemistry ACHIRAL
Molecular Formula C21H30N2O.C6H8O7
Molecular Weight 518.5992
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BUNAFTINE CITRATE

SMILES

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCCCN(CCN(CC)CC)C(=O)C1=CC=CC2=C1C=CC=C2

InChI

InChIKey=ROPZWLPGYFZSSN-UHFFFAOYSA-N
InChI=1S/C21H30N2O.C6H8O7/c1-4-7-15-23(17-16-22(5-2)6-3)21(24)20-14-10-12-18-11-8-9-13-19(18)20;7-3(8)1-6(13,5(11)12)2-4(9)10/h8-14H,4-7,15-17H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

HIDE SMILES / InChI
Bunaftine is a class III antiarrhythmic agent which has been found effective in treating or preventing both ventricular and supraventricular arrhythmias. The acute electrophysiologic effects of intravenous Bunaphtine 1,5 mg/kg body weight, were studied in 19 subjects with estimated normal impulse formation and conduction. Significant effects were sinus bradycardia, prolongation of atrial refractory periods, depression of intranodal and infranodal conduction and prolongation of His-Purkinje system refractory periods. These properties are compared with those of amiodarone and quinidine and form the basis for correct use of Bunaphtine in the management of arrhythmias

Approval Year

Name Type Language
BUNAFTINE CITRATE
MART.   MI  
Common Name English
BUNAPHTIDE CITRATE
Common Name English
MEREGON
Common Name English
1-NAPHTHALENECARBOXAMIDE, N-BUTYL-N-(2-(DIETHYLAMINO)ETHYL)-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (1:1)
Systematic Name English
BUNAFTINE CITRATE [MI]
Common Name English
BUNAFTINE CITRATE [MART.]
Common Name English
BUNAPHTINE CITRATE
Common Name English
Code System Code Type Description
MERCK INDEX
m1046
Created by admin on Fri Dec 15 17:16:19 GMT 2023 , Edited by admin on Fri Dec 15 17:16:19 GMT 2023
PRIMARY Merck Index
PUBCHEM
3086115
Created by admin on Fri Dec 15 17:16:19 GMT 2023 , Edited by admin on Fri Dec 15 17:16:19 GMT 2023
PRIMARY
FDA UNII
0A2V53992Z
Created by admin on Fri Dec 15 17:16:19 GMT 2023 , Edited by admin on Fri Dec 15 17:16:19 GMT 2023
PRIMARY
CAS
94157-87-6
Created by admin on Fri Dec 15 17:16:19 GMT 2023 , Edited by admin on Fri Dec 15 17:16:19 GMT 2023
PRIMARY
ECHA (EC/EINECS)
303-055-1
Created by admin on Fri Dec 15 17:16:19 GMT 2023 , Edited by admin on Fri Dec 15 17:16:19 GMT 2023
PRIMARY