Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C5H12NO5P |
| Molecular Weight | 197.1262 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=O)N(O)CCCP(O)(O)=O
InChI
InChIKey=PKMNDDZSIHLLLI-UHFFFAOYSA-N
InChI=1S/C5H12NO5P/c1-5(7)6(8)3-2-4-12(9,10)11/h8H,2-4H2,1H3,(H2,9,10,11)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Diaryl ester prodrugs of FR900098 with improved in vivo antimalarial activity. | 2001 Mar 26 |
|
| Synthesis and antimalarial activity of chain substituted pivaloyloxymethyl ester analogues of Fosmidomycin and FR900098. | 2006 Aug 1 |
|
| Cloning, expression, and biochemical characterization of Streptomyces rubellomurinus genes required for biosynthesis of antimalarial compound FR900098. | 2008 Aug 25 |
|
| Design, synthesis, and X-ray crystallographic studies of α-aryl substituted fosmidomycin analogues as inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase. | 2011 Jul 28 |
|
| DXR inhibition by potent mono- and disubstituted fosmidomycin analogues. | 2013 Aug 8 |
|
| Alpha-heteroatom derivatized analogues of 3-(acetylhydroxyamino)propyl phosphonic acid (FR900098) as antimalarials. | 2013 Jan 10 |
|
| The effect of chain length and unsaturation on Mtb Dxr inhibition and antitubercular killing activity of FR900098 analogs. | 2014 Jan 15 |
Patents
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| Code System | Code | Type | Description | ||
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162204
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0711Y106HV
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66508-32-5
Created by
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DTXSID50216710
Created by
admin on Sat Dec 16 10:58:41 GMT 2023 , Edited by admin on Sat Dec 16 10:58:41 GMT 2023
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ACTIVE MOIETY
