AVE-1330A FREE ACID

NC(=O)[C@@H]1CC[C@@H]2C[N@]1C(=O)N2OS(O)(=O)=O

InChIKey=NDCUAPJVLWFHHB-UHNVWZDZSA-N

InChI=1S/C7H11N3O6S/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15/h4-5H,1-3H2,(H2,8,11)(H,13,14,15)/t4-,5+/m1/s1

PubMed

Title	Date	PubMed
In vitro activity of the {beta}-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases.	2009 Aug	19493866
In vitro activity of avibactam (NXL104) in combination with β-lactams against Gram-negative bacteria, including OXA-48 β-lactamase-producing Klebsiella pneumoniae.	2012 Jan	22041508
Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor.	2012 Jul 17	22753474
Kinetics of avibactam inhibition against Class A, C, and D β-lactamases.	2013 Sep 27	23913691
In vivo efficacy of humanized exposures of Ceftazidime-Avibactam in comparison with Ceftazidime against contemporary Enterobacteriaceae isolates.	2014 Nov	25223999
Role of the Outer Membrane and Porins in Susceptibility of β-Lactamase-Producing Enterobacteriaceae to Ceftazidime-Avibactam.	2015 Dec 14	26666933
Randomized pharmacokinetic and drug-drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects.	2015 Oct	26516584

Name

Type

Language

AVE-1330A FREE ACID

Common Name

English

1,6-DIAZABICYCLO(3.2.1)OCTANE-2-CARBOXAMIDE, 7-OXO-6-(SULFOOXY)-, (1R,2S,5R)-REL-

Systematic Name

English

AVIBACTAM, (±)-

Common Name

English

Code System Code Type Description

CAS

396731-14-9

Created by admin on Sat Dec 16 07:59:41 GMT 2023 , Edited by admin on Sat Dec 16 07:59:41 GMT 2023

PRIMARY

FDA UNII

06MFO7817I

Created by admin on Sat Dec 16 07:59:41 GMT 2023 , Edited by admin on Sat Dec 16 07:59:41 GMT 2023

PRIMARY

PUBCHEM

9835049

Created by admin on Sat Dec 16 07:59:41 GMT 2023 , Edited by admin on Sat Dec 16 07:59:41 GMT 2023

PRIMARY

CAS

794508-22-8

Created by admin on Sat Dec 16 07:59:41 GMT 2023 , Edited by admin on Sat Dec 16 07:59:41 GMT 2023

SUPERSEDED

ACTIVE MOIETY


					06MFO7817I