Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C6H13NO2 |
| Molecular Weight | 131.1729 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC[C@@H](C)[C@H](N)C(O)=O
InChI
InChIKey=AGPKZVBTJJNPAG-UHNVWZDZSA-N
InChI=1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5+/m1/s1
L-alloisoleucine (2S, 3R), a diastereomer of L-isoleucine (2S, 3S), is a normal constituent of human plasma. It was shown, that the plasma L-alloisoleucine above the cutoff value of 5 micromol/L is the most specific and most sensitive diagnostic marker for all forms of maple syrup urine disease (MSUD). The precise mechanism of L-alloisoleucine formation is unclear, but existed suggestions, that R-3-methyl-2-oxopentanoate is an immediate and inevitable byproduct of L-isoleucine transamination and that alloisoleucine is primarily formed via transamination of 3-methyl-2-oxopenanoate in vivo.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The role of coupled positive feedback in the expression of the SPI1 type three secretion system in Salmonella. | 2010-07-29 |
|
| [Surgical complications of renal transplantation from living donors: experience of the CHU Ibn Sina, Rabat]. | 2010 |
|
| What is a microsatellite: a computational and experimental definition based upon repeat mutational behavior at A/T and GT/AC repeats. | 2010 |
|
| Imaging improves diagnosis of dementia with lewy bodies. | 2009-12 |
|
| Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes. | 2009-08-04 |
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| Incidence of lower-limb amputation in the diabetic and nondiabetic general population: a 10-year population-based cohort study of initial unilateral and contralateral amputations and reamputations. | 2009-02 |
|
| Rho-kinase-dependent F-actin rearrangement is involved in the inhibition of PI3-kinase/Akt during ischemia-reperfusion-induced endothelial cell apoptosis. | 2008-03 |
|
| Enantioselective and diastereoselective separation of synthetic pyrethroid insecticides on a novel chiral stationary phase by high-performance liquid chromatography. | 2007-07 |
|
| Salmonella invasion gene regulation: a story of environmental awareness. | 2005-02 |
|
| Studies on the biosynthesis of asperparaline A: origin of the spirosuccinimde ring system. | 2003-12-03 |
|
| [Dynamics of infection of Fringilla coelebs chaffinch nestlings with feather mites (Acari: Analgoidea)]. | 2002-12-17 |
Patents
| Name | Type | Language | ||
|---|---|---|---|---|
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Preferred Name | English | ||
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Systematic Name | English | ||
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Systematic Name | English | ||
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Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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3107-04-8
Created by
admin on Mon Mar 31 22:51:40 GMT 2025 , Edited by admin on Mon Mar 31 22:51:40 GMT 2025
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05T3WT3PJ1
Created by
admin on Mon Mar 31 22:51:40 GMT 2025 , Edited by admin on Mon Mar 31 22:51:40 GMT 2025
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PRIMARY | |||
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DTXSID501019679
Created by
admin on Mon Mar 31 22:51:40 GMT 2025 , Edited by admin on Mon Mar 31 22:51:40 GMT 2025
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PRIMARY | |||
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221-464-2
Created by
admin on Mon Mar 31 22:51:40 GMT 2025 , Edited by admin on Mon Mar 31 22:51:40 GMT 2025
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PRIMARY |
SUBSTANCE RECORD
