Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C6H13NO2 |
| Molecular Weight | 131.1729 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC[C@@H](C)[C@H](N)C(O)=O
InChI
InChIKey=AGPKZVBTJJNPAG-UHNVWZDZSA-N
InChI=1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5+/m1/s1
| Molecular Formula | C6H13NO2 |
| Molecular Weight | 131.1729 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
L-alloisoleucine (2S, 3R), a diastereomer of L-isoleucine (2S, 3S), is a normal constituent of human plasma. It was shown, that the plasma L-alloisoleucine above the cutoff value of 5 micromol/L is the most specific and most sensitive diagnostic marker for all forms of maple syrup urine disease (MSUD). The precise mechanism of L-alloisoleucine formation is unclear, but existed suggestions, that R-3-methyl-2-oxopentanoate is an immediate and inevitable byproduct of L-isoleucine transamination and that alloisoleucine is primarily formed via transamination of 3-methyl-2-oxopenanoate in vivo.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Dynamics of infection of Fringilla coelebs chaffinch nestlings with feather mites (Acari: Analgoidea)]. | 2002 Sep-Oct |
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| Rho-kinase-dependent F-actin rearrangement is involved in the inhibition of PI3-kinase/Akt during ischemia-reperfusion-induced endothelial cell apoptosis. | 2008 Mar |
|
| Incidence of lower-limb amputation in the diabetic and nondiabetic general population: a 10-year population-based cohort study of initial unilateral and contralateral amputations and reamputations. | 2009 Feb |
|
| [Surgical complications of renal transplantation from living donors: experience of the CHU Ibn Sina, Rabat]. | 2010 |
|
| What is a microsatellite: a computational and experimental definition based upon repeat mutational behavior at A/T and GT/AC repeats. | 2010 |
|
| The role of coupled positive feedback in the expression of the SPI1 type three secretion system in Salmonella. | 2010 Jul 29 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:49:28 GMT 2023
by
admin
on
Sat Dec 16 09:49:28 GMT 2023
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| Record UNII |
05T3WT3PJ1
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| Record Status |
Validated (UNII)
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| Record Version |
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3107-04-8
Created by
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05T3WT3PJ1
Created by
admin on Sat Dec 16 09:49:28 GMT 2023 , Edited by admin on Sat Dec 16 09:49:28 GMT 2023
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DTXSID501019679
Created by
admin on Sat Dec 16 09:49:28 GMT 2023 , Edited by admin on Sat Dec 16 09:49:28 GMT 2023
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221-464-2
Created by
admin on Sat Dec 16 09:49:28 GMT 2023 , Edited by admin on Sat Dec 16 09:49:28 GMT 2023
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PRIMARY |