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Details

Stereochemistry ACHIRAL
Molecular Formula C12H4Br4O2
Molecular Weight 499.775
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2,3,7,8-TETRABROMODIBENZO-P-DIOXIN

SMILES

BrC1=CC2=C(OC3=CC(Br)=C(Br)C=C3O2)C=C1Br

InChI

InChIKey=JZLQUWSWOJPCAK-UHFFFAOYSA-N
InChI=1S/C12H4Br4O2/c13-5-1-9-10(2-6(5)14)18-12-4-8(16)7(15)3-11(12)17-9/h1-4H

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
In utero and lactational exposure to low doses of chlorinated and brominated dioxins induces deficits in the fear memory of male mice.
2010-08
Quantitative relationship between the octanol/water partition coefficient and the diffusion limitation of the exchange between adipose and blood.
2010-01-07
RE: "Mortality rates among trichlorophenol workers with exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin".
2010-01-01
Mortality rates among trichlorophenol workers with exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
2009-08-15
Differential induction of cytochrome P450 1A1 and 1B1 mRNA in primary cultured bovine hepatocytes treated with TCDD, PBDD/Fs and feed ingredients.
2009-03-28
Comparison of immunotoxicity among tetrachloro-, pentachloro-, tetrabromo- and pentabromo-dibenzo-p-dioxins in mice.
2009-02-04
Aryl hydrocarbon receptor-mediated down-regulation of sox9b causes jaw malformation in zebrafish embryos.
2008-12
A technical mixture of 2,2',4,4'-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity.
2008-09
Occurrence of two different types of glutathione S-transferase placental form-positive hepatocytes after a single administration of 2,3,7,8-tetrabromodibenzo-p-dioxin in rats.
2008-07
Styrene trimer may increase thyroid hormone levels via down-regulation of the aryl hydrocarbon receptor (AhR) target gene UDP-glucuronosyltransferase.
2008-06
Determination of brominated flame retardants and brominated dioxins in fish collected from three regions of Japan.
2008-02
Effects of brominated flame retardants and brominated dioxins on steroidogenesis in H295R human adrenocortical carcinoma cell line.
2007-04
Dose- and time-dependent effects of 2,3,7,8-tetrabromodibenzo-p-dioxin on rat liver.
2007-02
Heterogeneity of human adipose blood flow.
2007-01-20
Novel compound 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) prevents 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor.
2006-06
Systemic and myelotoxic effects of single administration of 2,3,7,8-tetrabromodibenzo-p-dioxin in rats.
2006-05
Validation of Haber's Rule (dose x time = constant) in rats and mice for monochloroacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin under conditions of kinetic steady state.
2005-11-05
Four-way data coupled to parallel factor model applied to environmental analysis: determination of 2,3,7,8-tetrachloro-dibenzo-para-dioxin in highly contaminated waters by solid-liquid extraction laser-excited time-resolved Shpol'skii spectroscopy.
2005-04-15
Photodegradation of tetra- and hexachlorodibenzo-p-dioxins.
2005-04-11
A carbohydrate fraction, AIP1, from Artemisia iwayomogi down-regulates Fas gene expression and suppresses apoptotic death of the thymocytes induced by 2,3,7,8-tectrachlorodibenzo-p-dioxin.
2005-02
Analysis of Ah receptor pathway activation by brominated flame retardants.
2004-06
Brominated dioxin-like compounds: in vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds.
2003-09
Short- and long-term morbidity and mortality in the population exposed to dioxin after the "Seveso accident".
2003-07
Name Type Language
2,3,7,8-TBDD
Preferred Name English
2,3,7,8-TETRABROMODIBENZO-P-DIOXIN
Common Name English
2,3,7,8-TETRABROMODIBENZODIOXIN
Systematic Name English
Code System Code Type Description
FDA UNII
04PL7F455E
Created by admin on Mon Mar 31 18:53:03 GMT 2025 , Edited by admin on Mon Mar 31 18:53:03 GMT 2025
PRIMARY
CAS
50585-41-6
Created by admin on Mon Mar 31 18:53:03 GMT 2025 , Edited by admin on Mon Mar 31 18:53:03 GMT 2025
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MESH
C066841
Created by admin on Mon Mar 31 18:53:03 GMT 2025 , Edited by admin on Mon Mar 31 18:53:03 GMT 2025
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EPA CompTox
DTXSID6073524
Created by admin on Mon Mar 31 18:53:03 GMT 2025 , Edited by admin on Mon Mar 31 18:53:03 GMT 2025
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PUBCHEM
39729
Created by admin on Mon Mar 31 18:53:03 GMT 2025 , Edited by admin on Mon Mar 31 18:53:03 GMT 2025
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CHEBI
77565
Created by admin on Mon Mar 31 18:53:03 GMT 2025 , Edited by admin on Mon Mar 31 18:53:03 GMT 2025
PRIMARY