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Details

Stereochemistry ACHIRAL
Molecular Formula C12H4Br4O2
Molecular Weight 499.775
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2,3,7,8-TETRABROMODIBENZO-P-DIOXIN

SMILES

BrC1=CC2=C(OC3=CC(Br)=C(Br)C=C3O2)C=C1Br

InChI

InChIKey=JZLQUWSWOJPCAK-UHFFFAOYSA-N
InChI=1S/C12H4Br4O2/c13-5-1-9-10(2-6(5)14)18-12-4-8(16)7(15)3-11(12)17-9/h1-4H

HIDE SMILES / InChI

Molecular Formula C12H4Br4O2
Molecular Weight 499.775
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
In utero and lactational exposure to low doses of chlorinated and brominated dioxins induces deficits in the fear memory of male mice.
2010-08
Quantitative relationship between the octanol/water partition coefficient and the diffusion limitation of the exchange between adipose and blood.
2010-01-07
RE: "Mortality rates among trichlorophenol workers with exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin".
2010-01-01
Mortality rates among trichlorophenol workers with exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
2009-08-15
Differential induction of cytochrome P450 1A1 and 1B1 mRNA in primary cultured bovine hepatocytes treated with TCDD, PBDD/Fs and feed ingredients.
2009-03-28
Comparison of immunotoxicity among tetrachloro-, pentachloro-, tetrabromo- and pentabromo-dibenzo-p-dioxins in mice.
2009-02-04
Aryl hydrocarbon receptor-mediated down-regulation of sox9b causes jaw malformation in zebrafish embryos.
2008-12
A technical mixture of 2,2',4,4'-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity.
2008-09
Occurrence of two different types of glutathione S-transferase placental form-positive hepatocytes after a single administration of 2,3,7,8-tetrabromodibenzo-p-dioxin in rats.
2008-07
Styrene trimer may increase thyroid hormone levels via down-regulation of the aryl hydrocarbon receptor (AhR) target gene UDP-glucuronosyltransferase.
2008-06
Determination of brominated flame retardants and brominated dioxins in fish collected from three regions of Japan.
2008-02
Effects of brominated flame retardants and brominated dioxins on steroidogenesis in H295R human adrenocortical carcinoma cell line.
2007-04
Dose- and time-dependent effects of 2,3,7,8-tetrabromodibenzo-p-dioxin on rat liver.
2007-02
Heterogeneity of human adipose blood flow.
2007-01-20
Novel compound 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) prevents 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor.
2006-06
Systemic and myelotoxic effects of single administration of 2,3,7,8-tetrabromodibenzo-p-dioxin in rats.
2006-05
Validation of Haber's Rule (dose x time = constant) in rats and mice for monochloroacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin under conditions of kinetic steady state.
2005-11-05
Four-way data coupled to parallel factor model applied to environmental analysis: determination of 2,3,7,8-tetrachloro-dibenzo-para-dioxin in highly contaminated waters by solid-liquid extraction laser-excited time-resolved Shpol'skii spectroscopy.
2005-04-15
Photodegradation of tetra- and hexachlorodibenzo-p-dioxins.
2005-04-11
A carbohydrate fraction, AIP1, from Artemisia iwayomogi down-regulates Fas gene expression and suppresses apoptotic death of the thymocytes induced by 2,3,7,8-tectrachlorodibenzo-p-dioxin.
2005-02
Analysis of Ah receptor pathway activation by brominated flame retardants.
2004-06
Brominated dioxin-like compounds: in vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds.
2003-09
Short- and long-term morbidity and mortality in the population exposed to dioxin after the "Seveso accident".
2003-07
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:53:03 GMT 2025
Edited
by admin
on Mon Mar 31 18:53:03 GMT 2025
Record UNII
04PL7F455E
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2,3,7,8-TBDD
Preferred Name English
2,3,7,8-TETRABROMODIBENZO-P-DIOXIN
Common Name English
2,3,7,8-TETRABROMODIBENZODIOXIN
Systematic Name English
Code System Code Type Description
FDA UNII
04PL7F455E
Created by admin on Mon Mar 31 18:53:03 GMT 2025 , Edited by admin on Mon Mar 31 18:53:03 GMT 2025
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CAS
50585-41-6
Created by admin on Mon Mar 31 18:53:03 GMT 2025 , Edited by admin on Mon Mar 31 18:53:03 GMT 2025
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MESH
C066841
Created by admin on Mon Mar 31 18:53:03 GMT 2025 , Edited by admin on Mon Mar 31 18:53:03 GMT 2025
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EPA CompTox
DTXSID6073524
Created by admin on Mon Mar 31 18:53:03 GMT 2025 , Edited by admin on Mon Mar 31 18:53:03 GMT 2025
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PUBCHEM
39729
Created by admin on Mon Mar 31 18:53:03 GMT 2025 , Edited by admin on Mon Mar 31 18:53:03 GMT 2025
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CHEBI
77565
Created by admin on Mon Mar 31 18:53:03 GMT 2025 , Edited by admin on Mon Mar 31 18:53:03 GMT 2025
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