Details
Stereochemistry | UNKNOWN |
Molecular Formula | C28H36O6 |
Molecular Weight | 468.5818 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 0 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCC(C)(OC1=CC=C(C=C1)C2(CCCCC2)C3=CC=C(OC(C)(CC)C(O)=O)C=C3)C(O)=O
InChI
InChIKey=BMOVQUBVGICXQN-UHFFFAOYSA-N
InChI=1S/C28H36O6/c1-5-26(3,24(29)30)33-22-14-10-20(11-15-22)28(18-8-7-9-19-28)21-12-16-23(17-13-21)34-27(4,6-2)25(31)32/h10-17H,5-9,18-19H2,1-4H3,(H,29,30)(H,31,32)
DescriptionSources: https://www.google.com/patents/US20110269141
Sources: https://www.google.com/patents/US20110269141
Clinofibrate is known as a fibrate therapeutic drug for hyperlipidemia.
Originator
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: Q07869 Gene ID: 5465.0 Gene Symbol: PPARA Target Organism: Homo sapiens (Human) Sources: http://www.springer.com/us/book/9781461475538 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Primary | LIPOCLIN Approved UseIt is usually used to treat hyperlipidemia. |
PubMed
Title | Date | PubMed |
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Effects of some hypolipidemic agents on biochemical values and hepatic peroxisomal enzymes in rats: comparison of probucol, CGA, KCD-232, MLM-160, AL-369 and clinofibrate with clofibrate. | 1987 Mar |
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A case of familial hypercholesterolemia; secession from LDL-apheresis by the drug treatment with potent statin and resin. | 2005 Sep |
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Flow cytometric evaluation of synergistic pro-apoptotic effects of statins and clofibrates in IM-9 human lymphoblasts. | 2007 Sep |
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4,4'-(Cyclo-hexane-1,1-di-yl)diphenol methanol solvate. | 2009 Jan 10 |
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In vitro evaluation of inhibitory effects of antidiabetic and antihyperlipidemic drugs on human carboxylesterase activities. | 2010 Dec |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: http://www.229877.com/article/2013/0823/33410.html
For adults, take 1 tablet (200mg of the active ingredient) at a time, 3 times a day.
Route of Administration:
Oral
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C98150
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ACTIVE MOIETY