U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C11H15N5O4
Molecular Weight 281.2679
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2'-O-METHYLADENOSINE

SMILES

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3N

InChI

InChIKey=FPUGCISOLXNPPC-IOSLPCCCSA-N
InChI=1S/C11H15N5O4/c1-19-8-7(18)5(2-17)20-11(8)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1

HIDE SMILES / InChI

Approval Year

Targets

Targets

PubMed

PubMed

TitleDatePubMed
Transfer RNA modifications and genes for modifying enzymes in Arabidopsis thaliana.
2010-09-14
Modifications in small interfering RNA that separate immunostimulation from RNA interference.
2008-03-01
RNA analysis by MEKC with LIF detection.
2007-11
Liver-targeted prodrugs of 2'-C-methyladenosine for therapy of hepatitis C virus infection.
2007-08-09
Development of an in vitro cleavage assay system to examine vaccinia virus I7L cysteine proteinase activity.
2005-08-16
Acidity of secondary hydroxyls in ATP and adenosine analogues and the question of a 2',3'-hydrogen bond in ribonucleosides.
2004-11-17
Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase.
2004-04-22
Use of nucleotide analogs by class I and class II CCA-adding enzymes (tRNA nucleotidyltransferase): deciphering the basis for nucleotide selection.
2003-08
The role of magnesium ions and 2'-hydroxyl groups in the VS ribozyme-substrate interaction.
2002-11-22
Antiviral activity of O'-methylated derivatives of adenine arabinoside.
1977-04-15
Name Type Language
2'-O-METHYLADENOSINE
Systematic Name English
ADENOSINE, 2'-O-METHYL-
Preferred Name English
Code System Code Type Description
MESH
C024341
Created by admin on Mon Mar 31 19:19:06 GMT 2025 , Edited by admin on Mon Mar 31 19:19:06 GMT 2025
PRIMARY
FDA UNII
02YX82IHZ5
Created by admin on Mon Mar 31 19:19:06 GMT 2025 , Edited by admin on Mon Mar 31 19:19:06 GMT 2025
PRIMARY
PUBCHEM
102213
Created by admin on Mon Mar 31 19:19:06 GMT 2025 , Edited by admin on Mon Mar 31 19:19:06 GMT 2025
PRIMARY
CAS
2140-79-6
Created by admin on Mon Mar 31 19:19:06 GMT 2025 , Edited by admin on Mon Mar 31 19:19:06 GMT 2025
PRIMARY
CHEBI
69426
Created by admin on Mon Mar 31 19:19:06 GMT 2025 , Edited by admin on Mon Mar 31 19:19:06 GMT 2025
PRIMARY
EPA CompTox
DTXSID50175671
Created by admin on Mon Mar 31 19:19:06 GMT 2025 , Edited by admin on Mon Mar 31 19:19:06 GMT 2025
PRIMARY