DESMETHYLCLOMIPRAMINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H21ClN2
Molecular Weight	300.826
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DESMETHYLCLOMIPRAMINE

Structure Search

SMILES

CNCCCN1C2=CC=CC=C2CCC3=C1C=C(Cl)C=C3

InChI

InChIKey=VPIXQGUBUKFLRF-UHFFFAOYSA-N

InChI=1S/C18H21ClN2/c1-20-11-4-12-21-17-6-3-2-5-14(17)7-8-15-9-10-16(19)13-18(15)21/h2-3,5-6,9-10,13,20H,4,7-8,11-12H2,1H3

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
serotonin uptake 20 Target ID: GO:0051610 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7393826	Inhibitor 8297
dopamine uptake 14 Target ID: GO:0090494 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7393826	Inhibitor 8297

PubMed

PubMed

Title	Date	PubMed
Orthostatic side effects of clomipramine and citalopram during treatment for depression.	1985	3929308
Delirious episodes induced by intravenous administration of clomipramine associated with an acute increase in its plasma concentrations.	2000 Dec	11145466

Patents

Patents

Name

Type

Language

DESMETHYLCLOMIPRAMINE

Common Name

English

NORCHLORIMIPRAMINE

Common Name

English

5H-DIBENZ(B,F)AZEPINE-5-PROPANAMINE, 3-CHLORO-10,11-DIHYDRO-N-METHYL-

Systematic Name

English

GP-38025

Code

English

Desmethylclomipramine [WHO-DD]

Common Name

English

Code System Code Type Description

CAS

303-48-0

Created by admin on Fri Dec 15 19:12:08 GMT 2023 , Edited by admin on Fri Dec 15 19:12:08 GMT 2023

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SMS_ID

100000181521

Created by admin on Fri Dec 15 19:12:08 GMT 2023 , Edited by admin on Fri Dec 15 19:12:08 GMT 2023

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FDA UNII

01DN47PPQG

Created by admin on Fri Dec 15 19:12:08 GMT 2023 , Edited by admin on Fri Dec 15 19:12:08 GMT 2023

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EVMPD

SUB195252

Created by admin on Fri Dec 15 19:12:08 GMT 2023 , Edited by admin on Fri Dec 15 19:12:08 GMT 2023

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PUBCHEM

622606

Created by admin on Fri Dec 15 19:12:08 GMT 2023 , Edited by admin on Fri Dec 15 19:12:08 GMT 2023

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EPA CompTox

DTXSID70952663

Created by admin on Fri Dec 15 19:12:08 GMT 2023 , Edited by admin on Fri Dec 15 19:12:08 GMT 2023

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WIKIPEDIA

Norclomipramine

Created by admin on Fri Dec 15 19:12:08 GMT 2023 , Edited by admin on Fri Dec 15 19:12:08 GMT 2023

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PARENT (METABOLITE ACTIVE)


					NUV44L116D

SUBSTANCE RECORD


					01DN47PPQG

DESMETHYLCLOMIPRAMINE