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trifarotene
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There is one exact (name or code) match for trifarotene
Status:
US Approved Rx
(2019)
Source:
NDA211527
(2019)
Source URL:
First approved in 2019
Source:
NDA211527
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Trifarotene is a novel first-in-class fourth-generation topical retinoid. It is a potent and selective RAR gamma-agonist. In multiple mouse models, trifarotene exhibited superior comedolytic, anti-inflammatory and depigmenting activity compared with other topical retinoids. In this 52-week study, trifarotene was safe, well-tolerated and effective in moderate facial and truncal acne. Trifarotene is in phase II clinical trial for the treatment of ichthyosis.
Showing 1 - 7 of 7 results
Status:
US Approved Rx
(2019)
Source:
NDA211527
(2019)
Source URL:
First approved in 2019
Source:
NDA211527
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Trifarotene is a novel first-in-class fourth-generation topical retinoid. It is a potent and selective RAR gamma-agonist. In multiple mouse models, trifarotene exhibited superior comedolytic, anti-inflammatory and depigmenting activity compared with other topical retinoids. In this 52-week study, trifarotene was safe, well-tolerated and effective in moderate facial and truncal acne. Trifarotene is in phase II clinical trial for the treatment of ichthyosis.
Status:
Investigational
Source:
NCT00413205: Phase 2 Interventional Completed Emphysema
(2007)
Source URL:
Class:
PROTEIN
Status:
Possibly Marketed Outside US
Source:
NCT02710747: Phase 4 Interventional Unknown status Heart Valve Disease
(2015)
Source URL:
Class:
PROTEIN
![Structure of Ethyl 4′-(2-acetoxyethoxy)-3′′-tert-butyl-4′′-(pyrrolidin-1-yl)[1,1′:3′,1′′]terphenyl-4-carboxylate](/img/352ba1a2-1179-4c66-bb7e-16882a89d711.svg?size=200&context=fvcqealyqr)
