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Search results for isavuconazole in Reference URL (approximate match)
Showing 1 - 1 of 1 results
Status:
US Approved Rx
(2015)
Source:
NDA207500
(2015)
Source URL:
First approved in 2015
Source:
NDA207500
Source URL:
Class (Stereo):
CHEMICAL (EPIMERIC)
Isavuconazole is an active form of isavuconazonium, a prodrug which is marketed under the name Cresemba. Isavuconazole inhibits lanosterol 14-alpha demethylase (or CYP51A1) and leads to the accumulation of ergosterol toxic precursors in the fungal cytoplasm. Isavuconazole is indicated for the treatment of invasive aspergillosis and invasive mucormycosis.
