U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
First approved in 2012

Class (Stereo):
CHEMICAL (ACHIRAL)



Picosulfuric acid (as sodium picosulfate) is a contact laxative, which is used in combination with: magnesium oxide, and anhydrous citric acid for cleansing of the colon as a preparation for colonoscopy in adults. Sodium picosulfate is a prodrug. It has no significant direct physiological effect on the intestine. But it is hydrolyzed by colonic bacteria to form an active metabolite: bis-(p-hydroxy-phenyl)-pyridyl-2-methane, BHPM, which acts directly on the colonic mucosa to stimulate colonic peristalsis
Status:
First approved in 1963
Source:
Topex Mint by Dentsply LLC. Professional Division Trading as Sultan Healthcare
Source URL:

Class:
POLYMER

structurally diverse
Status:
US Previously Marketed
Source:
21 CFR 310.545(a)(8)(ii) digestive aid senna
Source URL:

Class:
STRUCTURALLY DIVERSE

structurally diverse
Status:
US Previously Marketed
Source:
Castor Oil U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Castor Oil U.S.P.
Source URL:

Class:
STRUCTURALLY DIVERSE