U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

9β,10α,17α-pregna-4,6-diene-3,20-dione ((8S,9R,10S,13S,14S,17R)-17-Acetyl-10,13-dimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one) is an isomer of Dydrogesterone, a synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function. 9β,10α,17α-pregna-4,6-diene-3,20-dione is one of major impurities of dydrogesterone. The physiological and toxicological properties of this compound have not been evaluated in humans.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

6-Dehydroprogesterone (Pregna-4,6-diene-3,20-dione) is a synthetic derivative and natural metabolite of progesterone and major impurity of dehydrogesterone. 6-Dehydroprogesterone derivatives has been used in hormone replacement therapy for menopausal symptoms and in the treatment of gynecological disorders, but 6-Dehydroprogesterone has never marketed.