U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
US Previously Marketed
Source:
THIOSULFIL SULFAMETHIZOLE by AYER5T
(1961)
Source URL:
First approved in 1953

Class (Stereo):
CHEMICAL (ACHIRAL)



Sulfamethizole is an oral antiobiotic, which was used against urinary tract infections under the name Thiosulfil. Sulfamethizole blocks bacterial growth by inhibiting folic acid synthesis via enzyme called dihydropteroate synthase. The drug is no longer marketed in the USA.