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Search results for simeprevir in Code Comments (approximate match)
Showing 1 - 1 of 1 results
Status:
US Previously Marketed
Source:
OLYSIO by JANSSEN PRODS
(2013)
Source URL:
First approved in 2013
Source:
OLYSIO by JANSSEN PRODS
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor approved for the treatment of Chronic Hepatitis C (genotype 1 and 4). Inhibiting NS3/4A, simeprevir blocks viral replication. In in vitro assays simeprevir was potent against HCV genotype 1a and 1b. Simeprevir must not be administered as monotherapy and should only be prescribed with both peginterferon alfa and ribavirin.
