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Search results for tolmetin in Code Literal (approximate match)
Showing 1 - 2 of 2 results
Status:
US Approved Rx
(1994)
Source:
ANDA074473
(1994)
Source URL:
First approved in 1976
Source:
TOLECTIN by ORTHO MCNEIL JANSSEN
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Tolmetin is a nonsteroidal anti-inflammatory agent. It was marketed as Tolectin in USA. TOLECTIN (tolmetin sodium) is indicated for the relief of signs and symptoms of
rheumatoid arthritis and osteoarthritis. TOLECTIN is indicated in the treatment of
acute flares and the long-term management of the chronic disease.
TOLECTIN is also indicated for treatment of juvenile rheumatoid arthritis. The mode of action of tolmetin is not known. However, studies in laboratory animals and man have demonstrated that the anti-inflammatory action of tolmetin is not due to pituitary-adrenal stimulation. Tolmetin inhibits prostaglandin synthetase in vitro and lowers the plasma level of prostaglandin E in man. This reduction in prostaglandin synthesis may be responsible for the anti-inflammatory action.
Status:
US Approved Rx
(1994)
Source:
ANDA074473
(1994)
Source URL:
First approved in 1976
Source:
TOLECTIN by ORTHO MCNEIL JANSSEN
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Tolmetin is a nonsteroidal anti-inflammatory agent. It was marketed as Tolectin in USA. TOLECTIN (tolmetin sodium) is indicated for the relief of signs and symptoms of
rheumatoid arthritis and osteoarthritis. TOLECTIN is indicated in the treatment of
acute flares and the long-term management of the chronic disease.
TOLECTIN is also indicated for treatment of juvenile rheumatoid arthritis. The mode of action of tolmetin is not known. However, studies in laboratory animals and man have demonstrated that the anti-inflammatory action of tolmetin is not due to pituitary-adrenal stimulation. Tolmetin inhibits prostaglandin synthetase in vitro and lowers the plasma level of prostaglandin E in man. This reduction in prostaglandin synthesis may be responsible for the anti-inflammatory action.
