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Search results for daprodustat in Code Literal (approximate match)
Showing 1 - 1 of 1 results
Status:
US Previously Marketed
Source:
JESDUVROQ by GLAXOSMITHKLINE
(2023)
Source URL:
First approved in 2023
Source:
JESDUVROQ by GLAXOSMITHKLINE
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Daprodustat (DUVROQ) is a small molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase (PHD) developed by GlaxoSmithKline for the treatment of anaemia in patients with chronic kidney disease (CKD). Inhibition of PHD prevents degradation of hypoxia-inducible factor (HIF), leading to the production of erythropoietin and subsequent induction of erythropoiesis. In June, daprodustat received its first approval in Japan for the treatment of renal anaemia.
