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Search results for "esketamine" in WIKIPEDIA (exact match)
Showing 1 - 1 of 1 results
Status:
US Approved Rx
(2019)
Source:
NDA211243
(2019)
Source URL:
First approved in 1970
Source:
NDA211243
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Esketamine is an S(+)-enantiomer of ketamine. It is a nonselective, noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptor. A nasal spray, containing esketamine, was approved in 2019 for the treatment of treatment-resistant depression in adults, in conjunction with an oral antidepressant, and is marketed under tradename SPARAVATO. Esketamine is a schedule III drug product in the USA.
