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Search results for "dantrolene" in WIKIPEDIA (exact match)
Showing 1 - 1 of 1 results
Status:
US Approved Rx
(1974)
Source:
NDA017443
(1974)
Source URL:
First approved in 1974
Source:
NDA017443
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Dantrolene is a drug which was approved by FDA for the treatment of chronic spasticity and malignant hyperthermia (a rare life-threatening clinical syndrome). Dantrolene effect was shown both in vivo and in vitro and proved to be mediated by interaction with Ryanodine receptor 1. The drug has a potential for hepatotoxicity and should be used as indicated in the label.