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Search results for "abarelix" in WIKIPEDIA (exact match)
Showing 1 - 1 of 1 results
Status:
US Previously Marketed
Source:
PLENAXIS by SPECIALITY EUROPEAN
(2003)
Source URL:
First approved in 2003
Source:
PLENAXIS by SPECIALITY EUROPEAN
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Abarelix is a synthetic decapeptide antagonist to gonadotropin releasing hormone (GnRH). It is marketed by Praecis Pharmaceuticals as Plenaxis. Used in the palliative treatment of advanced prostate cancer. Abarelix is a luteinizing hormone agonist that results in suppression of testicular or follicular steroidogenesis. Abarelix binds to the gonadotropin releasing hormone receptor and acts as a a potent inhibitor of gonadotropin secretion. Praecis announced in June 2006 that it was voluntarily withdrawing the drug from the market.