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There is one exact (name or code) match for rimegepant

RIMEGEPANT

997WVV895X

Search for Structure

Status:

US Approved Rx (2020)

Source:

NDA212728

(2020)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=212728

First approved in 2020

Source:

NDA212728

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=212728

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Calcitonin gene-related peptide type 1 receptor

Conditions:

Bristol-Myers Squibb developed Rimegepant, also known as BMS-927711. Rimegepant is a potent, selective, competitive and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraine. Rimegepant has shown in vivo efficacy without vasoconstrictor effect; it is superior to placebo at several different doses (75 mg, 150 mg, and 300 mg) and has an excellent tolerability profile.

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RIMEGEPANT

997WVV895X

Search for Structure

Status:

US Approved Rx (2020)

Source:

NDA212728

(2020)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=212728

First approved in 2020

Source:

NDA212728

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=212728

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Calcitonin gene-related peptide type 1 receptor

Conditions:

Bristol-Myers Squibb developed Rimegepant, also known as BMS-927711. Rimegepant is a potent, selective, competitive and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraine. Rimegepant has shown in vivo efficacy without vasoconstrictor effect; it is superior to placebo at several different doses (75 mg, 150 mg, and 300 mg) and has an excellent tolerability profile.

M-AMINOPYRIDINE

69JE8P2L84

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one, (6S,9R)-

KJ8H86WCT7

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

Ethyl 4-[(2-aminopyridin-3-yl)amino]piperidine-1-carboxylate

Y8F4U6M2CP

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

2,3-BIS(METHOXYCARBONYL)PYRIDINE

72P05L7R5R

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

5,6,7,8-Tetrahydro-5-hydroxy-9H-cyclohepta[b]pyridin-9-one

3BUH5NQ3T3

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

1,3-Dihydro-2H-imidazo[4,5-b]pyridin-2-one

4CA99G2HRY

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one, (6R,9R)-

CY2WNK9LMV

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one, (6R,9S)-

HM875U82YP

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

9-((Triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-one, (S)-

K4HBV5JTB3

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

Structure of RIMEGEPANT

ABSOLUTE

Structure of M-AMINOPYRIDINE

ACHIRAL

M-AMINOPYRIDINE

Structure of 6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one, (6S,9R)-

ABSOLUTE

6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one, (6S,9R)-

Structure of Ethyl 4-[(2-aminopyridin-3-yl)amino]piperidine-1-carboxylate

ACHIRAL

Ethyl 4-[(2-aminopyridin-3-yl)amino]piperidine-1-carboxylate

Structure of 2,3-BIS(METHOXYCARBONYL)PYRIDINE

ACHIRAL

2,3-BIS(METHOXYCARBONYL)PYRIDINE

Structure of 5,6,7,8-Tetrahydro-5-hydroxy-9H-cyclohepta[b]pyridin-9-one

RACEMIC

5,6,7,8-Tetrahydro-5-hydroxy-9H-cyclohepta[b]pyridin-9-one

Structure of 1,3-Dihydro-2H-imidazo[4,5-b]pyridin-2-one

ACHIRAL

1,3-Dihydro-2H-imidazo[4,5-b]pyridin-2-one

Structure of 6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one, (6R,9R)-

ABSOLUTE

6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one, (6R,9R)-

Structure of 6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one, (6R,9S)-

ABSOLUTE

6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one, (6R,9S)-

Structure of 9-((Triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-one, (S)-

ABSOLUTE

9-((Triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-one, (S)-

Showing 1 - 10 of 59 results

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