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Restrict the search for momelotinib to a specific field?

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There is one exact (name or code) match for momelotinib

MOMELOTINIB

6O01GMS00P

Search for Structure

Status:

US Approved Rx (2023)

Source:

NDA216873

(2023)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=216873

First approved in 2023

Source:

NDA216873

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=216873

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Tyrosine-protein kinase JAK1

Tyrosine-protein kinase JAK2

Conditions:

Pancreatic cancer

Non-small cell lung cancer

Secondary myelofibrosis (post-polycythemia vera and post-essential thrombocythemia)

Primary myelofibrosis

Momelotinib (CYT387) is an ATP-competitive small molecule that potently inhibits JAK1/JAK2 kinases. Momelotinib is developing by Gilead Sciences for the oral treatment of pancreatic and non-small cell lung cancers, and myeloproliferative disorders (including myelofibrosis, essential thrombocythaemia and polycythaemia vera).

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MOMELOTINIB

6O01GMS00P

Search for Structure

Status:

US Approved Rx (2023)

Source:

NDA216873

(2023)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=216873

First approved in 2023

Source:

NDA216873

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=216873

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Tyrosine-protein kinase JAK1

Tyrosine-protein kinase JAK2

Conditions:

Pancreatic cancer

Non-small cell lung cancer

Secondary myelofibrosis (post-polycythemia vera and post-essential thrombocythemia)

Primary myelofibrosis

Momelotinib (CYT387) is an ATP-competitive small molecule that potently inhibits JAK1/JAK2 kinases. Momelotinib is developing by Gilead Sciences for the oral treatment of pancreatic and non-small cell lung cancers, and myeloproliferative disorders (including myelofibrosis, essential thrombocythaemia and polycythaemia vera).

Ethyl 3-(2-chloro-4-pyrimidinyl)benzoate

C5PS7X4P3Y

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

4-(2-(4-(3-OXOMORPHOLIN-4-YL)ANILINO)PYRIMIDIN-4-YL)BENZAMIDE

BLN91TFF2I

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

4-[2-[(4-Aminophenyl)amino]-4-pyrimidinyl]-N-(cyanomethyl)benzamide

D3N4Z27FYS

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

N-(CYANOMETHYL)-4-(2-((4-(3-OXO-4-MORPHOLINYL)PHENYL)AMINO)-4-PYRIMIDINYL)BENZAMIDE

98KDC0ZGX2

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

2-(N-(CARBOXYMETHYL)-4-((4-(4-(CYANOMETHYLCARBAMOYL)PHENYL)PYRIMIDIN-2-YL)AMINO)ANILINO)ACETIC ACID

6YKA80H48Z

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

BENZOIC ACID, 4-(2-((4-(3-OXO-4-MORPHOLINYL)PHENYL)AMINO)-4-PYRIMIDINYL)-

U2VN75VM3A

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

BENZAMIDE, N-(CYANOMETHYL)-4-(2-((4-((2-HYDROXYETHYL)AMINO)PHENYL)AMINO)-4-PYRIMIDINYL)-

SZ42NX7H5A

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

N-(2-AMINO-2-OXO-ETHYL)-4-(2-(4-MORPHOLINOANILINO)PYRIMIDIN-4-YL)BENZAMIDE

8S2RNK5CL2

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

4-(2-((4-(4-MORPHOLINYL)PHENYL)AMINO)-4-PYRIMIDINYL)BENZOIC ACID

TV28NF837I

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

Structure of MOMELOTINIB

ACHIRAL

Structure of Ethyl 3-(2-chloro-4-pyrimidinyl)benzoate

ACHIRAL

Ethyl 3-(2-chloro-4-pyrimidinyl)benzoate

Structure of 4-(2-(4-(3-OXOMORPHOLIN-4-YL)ANILINO)PYRIMIDIN-4-YL)BENZAMIDE

ACHIRAL

4-(2-(4-(3-OXOMORPHOLIN-4-YL)ANILINO)PYRIMIDIN-4-YL)BENZAMIDE

Structure of 4-[2-[(4-Aminophenyl)amino]-4-pyrimidinyl]-N-(cyanomethyl)benzamide

ACHIRAL

4-[2-[(4-Aminophenyl)amino]-4-pyrimidinyl]-N-(cyanomethyl)benzamide

Structure of N-(CYANOMETHYL)-4-(2-((4-(3-OXO-4-MORPHOLINYL)PHENYL)AMINO)-4-PYRIMIDINYL)BENZAMIDE

ACHIRAL

N-(CYANOMETHYL)-4-(2-((4-(3-OXO-4-MORPHOLINYL)PHENYL)AMINO)-4-PYRIMIDINYL)BENZAMIDE

Structure of 2-(N-(CARBOXYMETHYL)-4-((4-(4-(CYANOMETHYLCARBAMOYL)PHENYL)PYRIMIDIN-2-YL)AMINO)ANILINO)ACETIC ACID

ACHIRAL

2-(N-(CARBOXYMETHYL)-4-((4-(4-(CYANOMETHYLCARBAMOYL)PHENYL)PYRIMIDIN-2-YL)AMINO)ANILINO)ACETIC ACID

Structure of BENZOIC ACID, 4-(2-((4-(3-OXO-4-MORPHOLINYL)PHENYL)AMINO)-4-PYRIMIDINYL)-

ACHIRAL

BENZOIC ACID, 4-(2-((4-(3-OXO-4-MORPHOLINYL)PHENYL)AMINO)-4-PYRIMIDINYL)-

Structure of BENZAMIDE, N-(CYANOMETHYL)-4-(2-((4-((2-HYDROXYETHYL)AMINO)PHENYL)AMINO)-4-PYRIMIDINYL)-

ACHIRAL

BENZAMIDE, N-(CYANOMETHYL)-4-(2-((4-((2-HYDROXYETHYL)AMINO)PHENYL)AMINO)-4-PYRIMIDINYL)-

Structure of N-(2-AMINO-2-OXO-ETHYL)-4-(2-(4-MORPHOLINOANILINO)PYRIMIDIN-4-YL)BENZAMIDE

ACHIRAL

N-(2-AMINO-2-OXO-ETHYL)-4-(2-(4-MORPHOLINOANILINO)PYRIMIDIN-4-YL)BENZAMIDE

Structure of 4-(2-((4-(4-MORPHOLINYL)PHENYL)AMINO)-4-PYRIMIDINYL)BENZOIC ACID

ACHIRAL

4-(2-((4-(4-MORPHOLINYL)PHENYL)AMINO)-4-PYRIMIDINYL)BENZOIC ACID

Showing 1 - 10 of 26 results

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