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38

Investigational

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Cannabinoid CB2 receptor

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Cannabinoid receptor 1

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University of Sydney

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Search results for "Wikipedia|List of designer drugs|Synthetic cannabinoids|Indole based" in comments (approximate match)

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ORG-28611

1U7V49NTQG

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Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Cannabinoid CB1 receptor

Conditions:

ORG-28611 (SCH-900,111) is a potent cannabinoid receptor full agonist, developed by Organon International for treatment pain. In preclinical studies, Org 28611 exhibited high affinity for both CB1 and CB2 cannabinoid receptors, as determined by radi...

oligand competition binding assays and rapidly metabolized by mouse and human hepatic microsomes and showed higher total levels in the brain compared to plasma. In clinical trials, Org 28611 does not provide enough sedation for outpatient surgical procedures, does not induce anterograde amnesia and causes undesirable subjective effects at higher doses. However, bolus doses up to 3 μ/kg (with maximum initial plasma concentrations of 24 ng/mL) or mean plasma levels up to 4 ng/mL are well tolerated and make it worthwhile to further explore the analgesic or antiemetic properties.

NNL-2

R5CLJ9ZS5H

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

BZODZ-EPYR

WSQ49D7D2Q

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Other

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CHEMICAL (ACHIRAL)

AMB-CHMICA

G6UJ3QB79J

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Class (Stereo):

CHEMICAL (RACEMIC)

4F-MDMB-BICA

FVN7GWR8S7

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Class (Stereo):

CHEMICAL (ABSOLUTE)

MDMB-FUBICA

K53ZMB4NR6

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Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

5-FLUORO EMB-PICA

ZWF7RX4ZHP

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Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

ADB-BICA

MM6K732EQE

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Class (Stereo):

CHEMICAL (RACEMIC)

SGT-151

CUT2RV7EIQ

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Class (Stereo):

CHEMICAL (ACHIRAL)

MDMB-CHMICA

X6JI7EA6EJ

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Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

Showing 1 - 10 of 39 results

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