Inxight Drugs

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52

Investigational

2

US Previously Marketed

2

Possibly Marketed Outside US

1

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Primary Target

Dopamine transporter

6

Norepinephrine transporter

6

Serotonin transporter

6

5-hydroxytryptamine receptor 2A

3

5-hydroxytryptamine receptor 1A

2

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Highest Phase

Approved

1

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Approval Year

Unknown

55

1949

1

1961

1

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Condition

Depression

2

Unknown

2

Bipolar disorder

1

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Primary

2

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CNS Activity

CNS Active

3

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Originator

Alles, G.A.

1

Eli Lilly

1

The Upjohn Company

1

Upjohn

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Chemical

57

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FDA UNII

57

PUBCHEM

57

WIKIPEDIA

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CAS

56

EPA CompTox

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Search results for "Wikipedia|List of designer drugs|Empathogens" in comments (approximate match)

Showing 1 - 10 of 57 results

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PARA-BROMOAMPHETAMINE

6IBU62D1N2

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Status:

Investigational

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

Monoamine oxidase

INDOPAN

BIK35ACJ0Q

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Status:

Investigational

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

Amine oxidase, copper containing

Monoamine oxidase A

Conditions:

Bipolar disorder

Alpha methyltryptamine (AMT) is a tryptamine (indole ethylamine) derivative, which was developed in the 1960's by Upjohn with the intention for use as an antidepressant. It was used in Russia under the trade name Indopan for the treatment of Bipolar ...

disorder and some form of depression, but currently not being produced because of serious side effects. In the 1990's, alpha-methyltryptamine became regulated as a Schedule I controlled substance in the United States. Pharmacologically, AMT has high affinity for the serotonin (5-HT) transporter, a number of 5-HT receptors, and potently inhibits reuptake of monoamines dopamine, 5-HT, and norepinephrine reuptake. AMT is also a monoamine oxidase A inhibitor that conceivably could contribute to its pharmacological effect and this drug also the most potent inhibitor of semicarbazide-sensitive amine oxidase (SSAO).

5-APB

2M3825704H

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Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

Norepinephrine transporter

Serotonin transporter

Dopamine transporter

Conditions:

5-(2-Aminopropyl)benzofuran (5-APB) is an empathogenic psychoactive compound of the substituted benzofuran, substituted amphetamine and substituted phenethylamine classes. 5-(2-Aminopropyl)benzofuran is a serotonin–norepinephrine–dopamine reuptake in...

hibitor and serotonin–norepinephrine–dopamine releasing agent. The toxicity and long-term health effects of recreational 5-APB use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown/ 5-(2-Aminopropyl)benzofuran 's high affinity for the 5-HT2b receptor makes it likely that 5-APB would be cardiotoxic with long-term use, as seen in other 5-HT2B agonists such as fenfluramine and MDMA.

DIBUTYLONE

3ZLY5MSD6N

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Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

4-FLUOROSELEGILINE

6U6PT7CR42

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Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

3-FLUOROETHAMPHETAMINE

YBV3PB8WOZ

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Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

MMDA-2

TG0B6ER184

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Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

METHAMNETAMINE

CAS64BB01B

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Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

5-METHOXY-.ALPHA.-ETHYLTRYPTAMINE

QCQ6JFX5NL

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Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

N-METHYLINDAN-2-AMINE

ZLW84Y27HG

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium-dependent noradrenaline transporter

5-hydroxytryptamine receptor 1A

Trace amine-associated receptor 1

Alpha-2A adrenergic receptor

norepinephrine secretion

5-hydroxytryptamine receptor 2A

Showing 1 - 10 of 57 results

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