U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Showing 1 - 10 of 32 results

Status:
US Approved Rx (2023)
First approved in 2008

Class (Stereo):
CHEMICAL (ACHIRAL)



Plerixafor is a bicyclam molecule, which has been identified as a specific antagonist of CXCR4. It had originally been developed as an inhibitor of T-tropic human immunodeficiency virus, but later demonstrated to be an effective mobilizer of hematop...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)



Pidotimod is a synthetic dipeptide with immunomodulatory properties. An immunostimulant used in patients with cell-mediated immunodepression during resp and urinary tract infections. In vitro and in vivo laboratory studies show that treatment with pi...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)



Roquinimex (Linomide, LS 2616) is a quinoline-3-carboxamide with pleiotropic immune modulating capacity and it has therapeutic effects in several experimental animal models of autoimmune diseases. Linomide has been evaluated in clinical trials for mu...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)



Cridanimod (Virexxa) is a small-molecule immunomodulator and interferon inducer, which, in preliminary studies, has been shown to increase progesterone receptor expression in endometrial tissue. Restoration of progesterone receptor expression may re-...
mixture
Status:
US Approved Rx (1989)
First approved in 1989

Class:
MIXTURE

mixture
Status:
Possibly Marketed Outside US

Class:
MIXTURE

Status:
US Approved Rx (2022)
First approved in 2002

Class:
PROTEIN

Status:
US Approved Rx (2002)
First approved in 2002

Class:
PROTEIN

Status:
US Approved Rx (2001)
First approved in 2001

Class:
PROTEIN

Status:
US Approved Rx (1996)
First approved in 1996

Class:
PROTEIN