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Showing 1 - 10 of 47 results

Status:
US Approved Rx (2003)
First approved in 2003

Class (Stereo):
CHEMICAL (RACEMIC)



Sertaconazole is a azole antifungal that is FDA approved for the treatment of interdigital tinea pedis in immunocompetent patients 12 years of age and older, caused by: Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum. S...
Status:
US Approved Rx (1996)
First approved in 1993

Class (Stereo):
CHEMICAL (ACHIRAL)



Butenafine is a synthetic antifungal agent that is structurally and pharmacologically related to allylamine antifungals. The exact mechanism of action has not been established, but it is suggested that butenafine's antifungal activity is exerted thro...
Status:
US Approved Rx (2007)
First approved in 1992

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Terbinafine (brand name Lamisil, Terbisil, Terboderm and others) is an antifungal medication used to treat ringworm and fungal nail infections. Terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the...
Status:
US Approved Rx (2009)
First approved in 1990

Class (Stereo):
CHEMICAL (ACHIRAL)



Fluconazole, a synthetic antifungal agent of the imidazole class, is used to treat vaginal candidiasis. It inhibits the fungal lanosterol 14 alpha-demethylase which thereby prevents the formation of ergosterol which is an essential component in the f...
Status:
US Approved Rx (1992)
First approved in 1988

Class (Stereo):
CHEMICAL (ACHIRAL)



Oxiconazole nitrate is 2',4'-dichloro-2-imidazol-1-ylacetophenone (Z)-[0-(2,4-dichlorobenzyl)oxime], mononitrate is an imidazole derivative characterized by a broad fungistatic spectrum. In vitro oxiconazole is highly effective against many dermato...
Status:
US Approved Rx (2019)
First approved in 1988

Class (Stereo):
CHEMICAL (ACHIRAL)



Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative. The following in vitro data are available, but their clinical significance is unknown. Naftifine has been shown to exhibit fungicidal activity in vitro against a br...
Status:
US Approved Rx (1985)
First approved in 1985

Class (Stereo):
CHEMICAL (RACEMIC)



Sulconazole (trade name Exelderm) is an antifungal medication of the imidazole class. Sulconazole has a broad spectrum of antifungal activity in vitro and has been shown to be an effective topical antifungal agent for the management of superficial fu...
Status:
US Approved Rx (1997)
First approved in 1983

Class (Stereo):
CHEMICAL (RACEMIC)



Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. Tioconazole is a broad-spectrum imidazole antifungal agent that inhibits the growth of human pathogenic yeasts. Tioconazole exhibits ...
Status:
US Approved Rx (2010)
First approved in 1982

Class (Stereo):
CHEMICAL (ACHIRAL)



Ciclopirox is an antifungal medication indicated for the treatment of seborrheic dermatitis (Loprox trade name) and onychomycosis of fingernails and toenails due to Trichophyton rubrum (Penlac trade name). The drug exerts its action by chelating Fe3+...
Status:
US Approved Rx (2002)
First approved in 1982

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Econazole (commonly used as the nitrate salt) is an antifungal medication of the imidazole class. It is a broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally....