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Showing 1 - 10 of 10 results

Status:
US Approved Rx (2010)
First approved in 2000

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Articaine is a dental local anesthetic, which is the most widely used in a number of European countries and is available in many countries around the world. Articaine in combination with epinephrine under the brand name Septocaine is indicated for lo...
Status:
US Approved Rx (2024)
First approved in 1996

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Ropivacaine is a member of the amino amide class of local anesthetics and is supplied as the pure S-(-)-enantiomer. It produces effects similar to other local anesthetics via reversible inhibition of sodium ion influx in nerve fibers. Ropivacaine is ...
Status:
US Approved Rx (1988)
First approved in 1972

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Bupivacaine is a widely used local anesthetic agent. Bupivacaine is often administered by spinal injection prior to total hip arthroplasty. It is also commonly injected into surgical wound sites to reduce pain for up to 20 hours after surgery. In com...
Status:
US Approved Rx (2003)
First approved in 1965

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Prilocaine is a local anesthetic that is similar pharmacologically to lidocaine. Prilocaine binds to the intracellular surface of sodium channels which blocks the subsequent influx of sodium into the cell. Action potential propagation and never funct...
Status:
US Approved Rx (1986)
First approved in 1960

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Mepivicaine is a local anesthetic of the amide type. Mepivicaine as a reasonably rapid onset and medium duration and is known by the proprietary names as Carbocaine and Polocaine. Mepivicaine is used in local infiltration and regional anesthesia. Sys...
Status:
US Approved OTC
First approved in 1948

Class (Stereo):
CHEMICAL (ACHIRAL)



Lidocaine is a local anesthetic and cardiac depressant used to numb tissue in a specific area and for management of cardiac arrhythmias, particularly those of ventricular origins, such as occur with acute myocardial infarction. Lidocaine alters signa...
Status:
US Approved OTC
First marketed in 1930

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Dibucaine is used as a local anesthetic for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. Dibucaine is used to temporarily relieve pain and i...
Status:
US Previously Marketed
First approved in 1999

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Levobupivacaine (CHIROCAINE®) is a (S)-enantiomer of bupivacaine and it is related chemically and pharmacologically to the amino amide class of local anesthetics. Local anesthetics block the generation and the conduction of nerve impulses by increasi...
Status:
US Previously Marketed
First approved in 1976

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Etidocaine, marketed under the trade name Duranest, is a local anesthetic given by injection during surgical procedures and labor and delivery. Etidocaine has a long duration of activity, and the main disadvantage of using during dentistry is increas...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Butanilicaine (Hostacain) is a local anesthetic. It uses may associate with a risk of allergy. Butanilicaine has a vasodilator effect.