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Search results for "ORPHAN DRUG|Designated|Treatment of stage IIB through IV melanoma" in comments (approximate match)
Showing 1 - 2 of 2 results
Status:
US Approved Rx
(2023)
Source:
NDA217110
(2023)
Source URL:
First approved in 1964
Source:
ALKERAN by APOTEX
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Melphalan, also known as L-phenylalanine mustard, phenylalanine mustard, L-PAM, or L-sarcolysin, is a phenylalanine derivative of nitrogen mustard. Melphalan is a bifunctional alkylating agent which produces a number of DNA adducts with the DNA interstrand crosslink (ICL) considered to be the critical cytotoxic lesion. Melphalan is used to treat different cancers including myeloma, melanoma and ovarian cancer.
Status:
Investigational
Source:
NCT00074737: Phase 2 Interventional Completed Acute Myelogenous Leukemia
(2004)
Source URL:
Class:
NUCLEIC ACID
