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Showing 1 - 10 of 249 results

Status:
US Approved Rx (2015)
First approved in 2015

Class (Stereo):
CHEMICAL (ABSOLUTE)



Uridine triacetate (formally PN401) is an acetylated prodrug of uridine. Following oral administration, uridine triacetate is deacetylated by nonspecific esterases present throughout the body, yielding uridine in the circulation. Uridine triacetate u...
Status:
US Approved Rx (2016)
First approved in 2014

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Dehydroepiandrosterone (INTRAROSA™, prasterone) is a major C19 steroid produced from cholesterol by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (INTRAROSA, prasterone) is structurall...
Status:
US Approved Rx (2019)
First approved in 2007

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Sapropterin dihydrochloride, the active pharmaceutical ingredient in Kuvan Tablets, is a synthetic preparation of the dihydrochloride salt of naturally occurring tetrahydrobiopterin (BH4). Kuvan is indicated to reduce blood phenylalanine (Phe) levels...
Status:
US Approved Rx (2017)
First approved in 2004

Class (Stereo):
CHEMICAL (ABSOLUTE)



Glutamine is a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important ener...
Status:
US Approved Rx (2002)
First approved in 2002

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Sodium oxybate is the sodium salt of gamma-hydroxybutyrate (GHB), an endogenous metabolite of gamma-aminobutyric acid (GABA) a major inhibitory neurotransmitter. Evidence suggests a role for GHB as a neuromodulator/neurotransmitter. Under endogenous ...
Status:
US Approved Rx (1998)
First approved in 1981

Class (Stereo):
CHEMICAL (ABSOLUTE)



Ecraprost [AS 013, Circulase] is a prodrug of prostaglandin E(1) within lipid microspheres that is being developed in Japan by Mitsubishi Pharma Corporation and Asahi Glass. It was originally in development with Welfide Corporation. On 1 October 2001...
Status:
US Approved Rx (1992)
First approved in 1977

Class (Stereo):
CHEMICAL (ABSOLUTE)



Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). Dinoprostone is equivalent to prostaglandin E2 (PGE2). It stimulates labor and delivery by stimulating the uterine, and thus terminates pregnancy. Dinoprostone is also capable of stimulat...
Status:
US Approved Rx (2018)
First approved in 1974

Class (Stereo):
CHEMICAL (ACHIRAL)



Dopamine, a sympathomimetic amine vasopressor, is the naturally occurring immediate precursor of norepinephrine. G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the physiological functions of the catecholaminergic neurotr...
Status:
US Approved Rx (2019)
First approved in 1970

Class (Stereo):
CHEMICAL (ABSOLUTE)



Levodopa (L-DOPA) was first isolated from seedlings of Vicia faba by Marcus Guggenheim in 1913. Levodopa, a dopamine precursor, is an effective and well-tolerated dopamine replacement agent used to treat Parkinson's disease. Oral levodopa has been wi...
Status:
US Approved Rx (1997)
First approved in 1966

Class (Stereo):
CHEMICAL (ABSOLUTE)



Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy. It is a disaccharide (double-sugar) formed from one molecule each of the simple sugars (monosaccharides) fructose and galactose. Lactulose is not no...